PDF(Pubmed)
Abstract：
UNASSIGNED: Despite the remarkable progress in minimally invasive surgery, the potential association between laparoscopic gastrectomy and the risk of peritoneal metastasis remains uncertain.
UNASSIGNED: To investigate variations in tumour markers in intraperitoneal drainage fluid between laparoscopic radical gastrectomy and open radical gastrectomy for gastric cancer.
UNASSIGNED: A total of 106 patients diagnosed with gastric cancer between July 2018 and November 2020 were included in this study, 45 of whom underwent laparoscopic radical gastrectomy (laparoscopic group) and 61 underwent open radical gastrectomy (open group). Variations in the levels of carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), cancer antigen 199 (CA199), and α-fetoprotein (AFP) in the intraperitoneal drainage fluid were compared and analysed on postoperative days (PODs) 1, 2, 3, and 5 between the two groups. Additionally, the postoperative 3-year survival rates between the two groups were compared and analysed.
UNASSIGNED: No significant differences in CEA, CA199, and AFP levels in the intraperitoneal drainage fluid were observed between the two groups on postoperative days (PODs) 1, 2, 3, and 5 (p > 0.05). However, the level of CA125 in the intraperitoneal drainage fluid of the laparoscopic group was notably higher than that of the open group on POD 2 (p < 0.05); however, there were no significant differences between the two groups on PODs 1, 3, and 5 (p > 0.05). There was no significant difference in the 3-year postoperative survival rates between the two groups.
UNASSIGNED: There were no significant differences in CEA, CA125, CA199, and AFP levels in the intraperitoneal drainage fluid between laparoscopic radical gastrectomy and open radical gastrectomy for gastric cancer, confirming from another perspective that laparoscopic radical gastrectomy does not increase the risk of intraperitoneal metastasis.
UNASSIGNED: To investigate variations in tumour markers in intraperitoneal drainage fluid between laparoscopic radical gastrectomy and open radical gastrectomy for gastric cancer.
UNASSIGNED: A total of 106 patients diagnosed with gastric cancer between July 2018 and November 2020 were included in this study, 45 of whom underwent laparoscopic radical gastrectomy (laparoscopic group) and 61 underwent open radical gastrectomy (open group). Variations in the levels of carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), cancer antigen 199 (CA199), and α-fetoprotein (AFP) in the intraperitoneal drainage fluid were compared and analysed on postoperative days (PODs) 1, 2, 3, and 5 between the two groups. Additionally, the postoperative 3-year survival rates between the two groups were compared and analysed.
UNASSIGNED: No significant differences in CEA, CA199, and AFP levels in the intraperitoneal drainage fluid were observed between the two groups on postoperative days (PODs) 1, 2, 3, and 5 (p > 0.05). However, the level of CA125 in the intraperitoneal drainage fluid of the laparoscopic group was notably higher than that of the open group on POD 2 (p < 0.05); however, there were no significant differences between the two groups on PODs 1, 3, and 5 (p > 0.05). There was no significant difference in the 3-year postoperative survival rates between the two groups.
UNASSIGNED: There were no significant differences in CEA, CA125, CA199, and AFP levels in the intraperitoneal drainage fluid between laparoscopic radical gastrectomy and open radical gastrectomy for gastric cancer, confirming from another perspective that laparoscopic radical gastrectomy does not increase the risk of intraperitoneal metastasis.
摘要：
■尽管微创手术取得了显著进展，腹腔镜胃切除术与腹膜转移风险之间的潜在关联仍不确定.
■探讨腹腔镜胃癌根治术与开腹胃癌根治术腹腔引流液中肿瘤标志物的变化。
■本研究共纳入了2018年7月至2020年11月期间诊断为胃癌的106例患者。其中45例行腹腔镜胃癌根治术(腹腔镜组),61例行开腹胃癌根治术(开腹组)。癌胚抗原（CEA）水平的变化，癌抗原125（CA125），癌抗原199（CA199），比较两组术后第1、2、3、5天腹腔引流液中的甲胎蛋白（AFP）。此外,比较并分析两组患者术后3年生存率。
■CEA没有显着差异，观察两组术后第1、2、3、5天的CA199、腹腔引流液中AFP水平(PODs)(p>0.05)。然而,腹腔镜组腹腔引流液中CA125水平明显高于开腹组(p<0.05);两组PODs1、3、5比较差异无统计学意义(p>0.05)。两组术后3年生存率差异无统计学意义。
■CEA没有显著差异，腹腔镜胃癌根治术与开腹胃癌根治术腹腔引流液中CA125、CA199、AFP水平,从另一个角度证实腹腔镜胃癌根治术不会增加腹膜内转移的风险。
■探讨腹腔镜胃癌根治术与开腹胃癌根治术腹腔引流液中肿瘤标志物的变化。
■本研究共纳入了2018年7月至2020年11月期间诊断为胃癌的106例患者。其中45例行腹腔镜胃癌根治术(腹腔镜组),61例行开腹胃癌根治术(开腹组)。癌胚抗原（CEA）水平的变化，癌抗原125（CA125），癌抗原199（CA199），比较两组术后第1、2、3、5天腹腔引流液中的甲胎蛋白（AFP）。此外,比较并分析两组患者术后3年生存率。
■CEA没有显着差异，观察两组术后第1、2、3、5天的CA199、腹腔引流液中AFP水平(PODs)(p>0.05)。然而,腹腔镜组腹腔引流液中CA125水平明显高于开腹组(p<0.05);两组PODs1、3、5比较差异无统计学意义(p>0.05)。两组术后3年生存率差异无统计学意义。
■CEA没有显著差异，腹腔镜胃癌根治术与开腹胃癌根治术腹腔引流液中CA125、CA199、AFP水平,从另一个角度证实腹腔镜胃癌根治术不会增加腹膜内转移的风险。
