TaqTth - hpRNA : 一种用于致病性 mRNA 特异性沉默的新型紧凑 RNA 靶向工具。
关键词: AAV APOE2 APP Alzheimer’s disease Hairpin RNA guiding probe RNA cleaving TaqTth
Mesh : RNA, Messenger / genetics metabolism Humans Alzheimer Disease / genetics metabolism Animals Gene Silencing Mice Amyloid beta-Protein Precursor / genetics metabolism RNA Cleavage Genetic Vectors Dependovirus / genetics
来 源:
DOI:10.1186/s13059-024-03326-3
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