关键词: COVID-19 COVID-19 vaccines advisory committee decision making health equity health policy immunization mRNA vaccines patient safety vaccination

来  源:   DOI:10.1016/j.acap.2024.06.019

Abstract:
Pediatricians and primary care providers serve an important role in building trust with families and communities. To support the critical role of front-line providers, this perspective seeks to reflect on the work of the Centers for Disease Control and Prevention\'s Advisory Committee on Immunization Practices to support COVID-19 pandemic response efforts. Although Advisory Committee on Immunization Practice (ACIP) recommends vaccines for all age groups, this perspective focuses on the pediatric lens and is tailored to Academic Pediatrics. ACIP adapted from in-person meetings 3 times yearly to virtual meetings on an emergency basis to ensure a thorough review and presentation of all the components of the evidence to recommendation framework, including explicit consideration of equity in the decision-making process. The need for diverse enrollment in clinical trials was highlighted as critical for supporting recommendations and enhancing trust. Near real-time vaccine safety surveillance was implemented at scale and emphasized the importance of collaboration between federal partners engaged in vaccine safety in the United States and extended to other countries with similar safety surveillance systems to enable early recognition and response to safety concerns. A key equity opportunity for future pandemics is to shorten the time between vaccines being available for adults and young children.
摘要:
儿科医生和初级保健提供者在与家庭和社区建立信任方面发挥着重要作用。为了支持前线供应商的关键作用,这一观点旨在反思疾病控制和预防中心(CDC)免疫实践咨询委员会的工作,以支持COVID-19大流行应对工作。虽然ACIP建议所有年龄组的疫苗,这种观点集中在儿科镜片上,是为学术儿科量身定制的.ACIP从每年3次的面对面会议改编为紧急会议的虚拟会议,以确保对“根据建议提出的证据”框架的所有组成部分进行彻底审查和介绍,包括在决策过程中明确考虑公平。强调了在临床试验中进行多样化注册的需求对于支持建议和增强信任至关重要。大规模实施了近乎实时的疫苗安全监测,并强调了在美国从事疫苗安全的联邦合作伙伴之间开展合作的重要性,并将其扩展到具有类似安全监测系统的其他国家,以实现对安全问题的早期识别和响应。未来大流行的一个关键公平机会是缩短成人和幼儿之间的疫苗供应时间。
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