关键词: Adenocarcinoma Case report Children Heredity Lymphoblastic leukemia

来  源:   DOI:10.1016/j.ijscr.2024.109995   PDF(Pubmed)

Abstract:
BACKGROUND: Colorectal cancer in children and adolescents is an exceptional condition. Its clinical symptoms are non-specific, leading to delayed diagnosis and poor prognosis.
METHODS: The present article reports the case of a 15-year-old child followed for acute lymphoblastic leukemia with a history of a grandfather operated on and followed for colorectal cancer. The child was admitted to our department with an occlusive syndrome. Endoscopy and radiological findings suggested the diagnosis of colon adenocarcinoma (AC). The therapeutic decision was a segmental colectomy covering the right colonic angle and colostomy followed by chemotherapy.
CONCLUSIONS: Colorectal cancer remains an exceptional pathology in children. They often include abdominal pain, nausea, vomiting and rectal discharge. Endoscopy is the key diagnostic test, enabling both distal and proximal lesions to be detected. Primary CA of the colon is rare in children, and even rarer as a second malignancy.
CONCLUSIONS: The clinical symptoms of colorectal adenocarcinoma in children are non-specific. These cancers are little-known in pediatrics, and are often diagnosed at an advanced stage.
摘要:
背景:儿童和青少年的结直肠癌是一种特殊情况。其临床症状是非特异性的,导致诊断延迟和预后不良。
方法:本文报道了一个15岁儿童因急性淋巴细胞白血病而随访的病例,该病例的病史为祖父做手术并随访结直肠癌。这个孩子因闭塞综合征入院。内窥镜检查和放射学检查结果提示诊断为结肠腺癌(AC)。治疗决定是覆盖右结肠角的节段性结肠切除术和结肠造口术,然后进行化疗。
结论:结直肠癌仍然是儿童的特殊病理。它们通常包括腹痛,恶心,呕吐和直肠排出。内窥镜检查是关键的诊断测试,能够检测远端和近端病变。原发性结肠CA在儿童中很少见,更罕见的是第二种恶性肿瘤。
结论:儿童大肠腺癌的临床症状是非特异性的。这些癌症在儿科中鲜为人知,通常在晚期被诊断出来。
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