Abstract：
This commentary article delves into the transformative role of optical coherence tomography angiography (OCTA) in diagnosing and managing a wide array of eye conditions, including diabetic retinopathy, age-related macular degeneration, retinal vein occlusions, and white dot syndromes. Developed in 2005, OCTA has emerged as a non-invasive, high-resolution imaging technique that offers advantages over traditional fluorescein angiography (FA), providing quicker and safer monitoring of ocular conditions with similar diagnostic accuracy. In diabetic retinopathy, OCTA has been instrumental in early identification of retinal changes, offering quantifiable metrics including perfused capillary density (PCD) for assessing vascular alterations. For age-related macular degeneration (AMD), OCTA has deepened our understanding of non-exudative neovascular AMD, allowing for more effective monitoring and potential earlier initiation of treatment. In cases of retinal vein occlusions, OCTA can reveal specific microvascular features and allow for depth-resolved measurements of the foveal avascular zone, providing significant prognostic implications. OCTA has also been invaluable in studying rare white dot syndromes, enabling nuanced differentiation between conditions that often present similarly. Emerging research also suggests that OCTA can have potential utility in neurodegenerative diseases like Alzheimer\'s, where retinal vascular patterns could offer diagnostic insights. While OCTA is revolutionizing ophthalmic care, further clinical trials and standardization are needed for its broader adoption into clinical practice.
摘要：
这篇评论文章探讨了光学相干断层扫描血管造影（OCTA）在诊断和管理各种眼部疾病中的转化作用，包括糖尿病视网膜病变，年龄相关性黄斑变性,视网膜静脉阻塞,和白点综合症。OCTA于2005年开发，已成为一种非侵入性，高分辨率成像技术，提供优于传统荧光素血管造影（FA），提供更快，更安全的眼部状况监测与类似的诊断精度。在糖尿病性视网膜病变中，OCTA有助于早期识别视网膜变化，提供可量化的指标，包括用于评估血管改变的灌注毛细血管密度（PCD）。对于年龄相关性黄斑变性（AMD），OCTA加深了我们对非渗出性新生血管性AMD的理解，允许更有效的监测和潜在的更早开始治疗。在视网膜静脉阻塞的情况下，OCTA可以揭示特定的微血管特征，并允许对中央凹无血管区进行深度分辨测量，提供显著的预后意义。OCTA在研究罕见的白点综合征方面也是无价的，在通常类似存在的条件之间实现细微差别。新兴的研究还表明，OCTA可以在神经退行性疾病如阿尔茨海默氏症中具有潜在的效用，视网膜血管模式可以提供诊断见解。虽然OCTA正在彻底改变眼科护理，需要进一步的临床试验和标准化才能将其更广泛地应用于临床实践.
