Abstract：
Polysubstance use is associated with myriad short- and long-term health outcomes. Although prior research has documented differences in polysubstance use between lesbian, gay, bisexual, transgender, queer/questioning, and other sexual and gender minoritized (LGBTQ +) youth and their heterosexual/cisgender counterparts, as well as between subgroups of LGBTQ + youth, it is unknown how personal, family, and school factors are associated with substance use patterns among LGBTQ + youth. Using a large, national sample of 9646 LGBTQ + youth ages 13-17, we used latent class analysis to examine patterns of alcohol, tobacco, and marijuana use and to determine whether personal, family, and school factors predict class membership. We identified five classes of substance use: polysubstance use, polysubstance experimentation, dual alcohol and cannabis, alcohol, and no use. Greater depression and LGBTQ + victimization, and an ability to be oneself at school, were associated with greater odds of membership in the polysubstance use class, while higher levels of family connection and having a Gender Sexuality Alliance (GSA) at school were associated with lower odds of membership in the polysubstance use class. Our analysis also revealed sociodemographic differences in class membership. These findings highlight potential mechanisms for intervention to reduce polysubstance use among LGBTQ + youth.
摘要：
多物质的使用与无数的短期和长期健康结果有关。尽管先前的研究已经记录了女同性恋之间在多物质使用方面的差异，同性恋,双性恋,变性人,酷儿/提问，以及其他性和性别化(LGBTQ+)青年及其异性恋/顺性者，以及LGBTQ+青年小组之间，这是未知的私人，家庭,学校因素与LGBTQ+青少年的物质使用模式有关。使用一个大的，全国样本9646名13-17岁的LGBTQ+青少年，我们使用潜在类别分析来检查酒精的模式，烟草,和大麻的使用，并确定是否个人，家庭,学校因素预测班级成员资格。我们确定了五类物质使用：多物质使用，多物质实验，酒精和大麻双重作用,酒精,也没用.更大的抑郁症和LGBTQ+受害，以及在学校做自己的能力，与加入多物质使用类的可能性更大相关，而更高水平的家庭联系和在学校拥有性别性联盟（GSA）与较低的多物质使用类成员资格相关。我们的分析还揭示了阶级成员的社会人口统计学差异。这些发现强调了干预减少LGBTQ+青少年多物质使用的潜在机制。
