关键词: Folliculitis Infection Intravenous drug use candida

来  源:   DOI:10.1016/j.jiac.2024.06.022

Abstract:
We present the case of a 53-year-old Caucasian man with a history of intravenous drug use who presented with fever and multiple pustules predominantly affecting hairy areas of the body, with no clinical improvement despite previous antibiotic treatment. Culture of the pustules confirmed Candida albicans infection and histological examination of skin biopsies revealed suppurative granulomas compatible with candidomycetic folliculitis. The patient was successfully treated with systemic antifungals and discharged with resolution of symptoms. Candidomycetic folliculitis is a condition typically associated with brown heroin consumption due to the use of acidic solvent that promotes Candida growth. Clinical manifestations include fever followed by skin lesions, with possible systemic involvement if untreated. Extensive folliculitis with associated fever in an IVDU should raise suspicion of this pathology since early diagnosis and appropriate treatment are crucial to prevent complications.
摘要:
我们介绍了一名53岁的高加索人,有静脉吸毒史,他表现为发烧和多发性脓疱,主要影响身体的毛状区域,尽管以前接受过抗生素治疗,但没有临床改善。脓疱的培养证实了白色念珠菌感染,皮肤活检的组织学检查显示化脓性肉芽肿与念珠菌毛囊炎相容。患者成功接受了全身性抗真菌药物治疗,症状缓解后出院。由于使用促进念珠菌生长的酸性溶剂,念珠菌毛囊炎通常与棕色海洛因消耗有关。临床表现包括发热和皮肤损伤,如果不治疗,可能有全身参与。IVDU中广泛的毛囊炎伴发热应引起对这种病理的怀疑,因为早期诊断和适当的治疗对于预防并发症至关重要。
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