Abstract：
Lichens have great potential as food, functional food additives or flavourings. The presence of specific substances with multiple biological activities is one of the characteristics of lichens. However, research on lichens as a food source or functional food additive is limited. The present study simulated, for the first time, the potential bioaccessibility of active compounds from 6 lichen species in simulated gastric and intestinal conditions. An in vitro digestion showed that the lichen substances had different bioaccessibility and stability during digestion. It was found that the application of some metabolic modulators significantly altered the accumulation of metabolites in most species. In addition, the study demonstrated the antimicrobial activity of the tested extracts as well as of 14 isolated lichen metabolites. These multi-directional studies demonstrate the potential of lichens in terms of their use as antimicrobial functional food additives.
摘要：
地衣作为食物有很大的潜力，功能性食品添加剂或调味剂。具有多种生物活性的特定物质的存在是地衣的特征之一。然而,地衣作为食品来源或功能性食品添加剂的研究是有限的。本研究模拟，第一次,在模拟的胃和肠道条件下，来自6种苔藓物种的活性化合物的潜在生物可及性。体外消化表明，地衣物质在消化过程中具有不同的生物可及性和稳定性。发现一些代谢调节剂的应用显着改变了大多数物种中代谢物的积累。此外,该研究证明了所测试提取物以及14种分离的地衣代谢物的抗菌活性。这些多方向研究证明了地衣在用作抗微生物功能食品添加剂方面的潜力。
