Abstract：
OBJECTIVE: Myeloproliferative neoplasm (MPN) burdens the lives of those affected. MPN patients endure significant impacts on their physical, psychological, and social well-being. While pharmacological interventions offer some disease and symptom control, they often have unfavorable side effects. This review explores the potential of Integrative Oncology (IO) therapies in managing MPNs and their associated symptoms.
RESULTS: IO is dedicated to augmenting conventional treatments through integrating interventions targeting the mind, body, nutrition, supplements, and other supportive care therapies. Several small studies suggest the benefit of an IO approach in MPN patients. These benefits are postulated to be modulated through enhanced physical capacity, reduced disease-related inflammation, subconscious mind training, and gut microbiome modulation. By combining IO with evidence-based pharmacological treatments, the potential exists to enhance the quality of life and clinical outcomes for individuals with MPNs. Future research should prioritize well-powered studies, including diverse demographics and symptom profiles, with appropriate study duration, to draw definite conclusions regarding the observed effects.
RESULTS: IO is dedicated to augmenting conventional treatments through integrating interventions targeting the mind, body, nutrition, supplements, and other supportive care therapies. Several small studies suggest the benefit of an IO approach in MPN patients. These benefits are postulated to be modulated through enhanced physical capacity, reduced disease-related inflammation, subconscious mind training, and gut microbiome modulation. By combining IO with evidence-based pharmacological treatments, the potential exists to enhance the quality of life and clinical outcomes for individuals with MPNs. Future research should prioritize well-powered studies, including diverse demographics and symptom profiles, with appropriate study duration, to draw definite conclusions regarding the observed effects.
摘要：
目的：骨髓增殖性肿瘤（MPN）加重患者的生命负担。MPN患者承受着对他们身体的重大影响，心理,和社会福祉。虽然药物干预提供了一些疾病和症状控制，它们经常有不利的副作用。这篇综述探讨了综合肿瘤学（IO）疗法在管理MPN及其相关症状方面的潜力。
结果：IO致力于通过整合针对大脑的干预措施来增强常规治疗，身体,营养,补充剂,和其他支持性护理疗法。一些小型研究表明IO方法对MPN患者的益处。这些好处被假定为通过增强身体能力来调节，减少疾病相关的炎症，潜意识训练，和肠道微生物组调节。通过将IO与循证药物治疗相结合，存在提高MPN患者生活质量和临床结局的潜力.未来的研究应该优先考虑有能力的研究，包括不同的人口统计和症状，在适当的研究持续时间内，就观察到的效果得出明确的结论。
结果：IO致力于通过整合针对大脑的干预措施来增强常规治疗，身体,营养,补充剂,和其他支持性护理疗法。一些小型研究表明IO方法对MPN患者的益处。这些好处被假定为通过增强身体能力来调节，减少疾病相关的炎症，潜意识训练，和肠道微生物组调节。通过将IO与循证药物治疗相结合，存在提高MPN患者生活质量和临床结局的潜力.未来的研究应该优先考虑有能力的研究，包括不同的人口统计和症状，在适当的研究持续时间内，就观察到的效果得出明确的结论。
