Mesh : Humans Insulinoma / diagnostic imaging Positron Emission Tomography Computed Tomography Embolization, Therapeutic Hypoglycemia Yttrium Radioisotopes / therapeutic use Gallium Radioisotopes Exenatide Heterocyclic Compounds, 1-Ring / therapeutic use Acetates Liver Neoplasms / secondary diagnostic imaging radiotherapy Pancreatic Neoplasms / diagnostic imaging radiotherapy Male Neoplasm Metastasis Middle Aged

来  源:   DOI:10.1097/RLU.0000000000005266

Abstract:
UNASSIGNED: Metastatic insulinomas can cause recurrent hypoglycemia requiring continuous IV glucose infusion. Various medical and chemotherapeutic treatment options are used to reduce the patient\'s risk of death due to hypoglycemia. Treatment-resistant hepatic metastatic insulinomas may benefit clinically from 90Y transarterial radioembolization therapy. In this case, we present a case of liver metastatic insulinoma that achieved clinical improvement after 2 cycles of 90Y microspheres transarterial radioembolization, and the presence of active metastases was demonstrated with 68Ga-NODAGA-exendin-4 PET/CT imaging.
摘要:
转移性胰岛素瘤可引起复发性低血糖,需要持续静脉输注葡萄糖。使用各种药物和化疗方案来降低患者因低血糖而死亡的风险。治疗抗性肝转移性胰岛素瘤可能在临床上受益于90Y经动脉放射栓塞治疗。在这种情况下,我们介绍了一例肝转移性胰岛素瘤,经过2个周期的90Y微球动脉放疗栓塞后,临床症状得到改善,68Ga-NODAGA-exendin-4PET/CT显像证实存在活动性转移。
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