Abstract:
Since ancient times, plants have been used as a remedy for numerous diseases. The pharmacological properties of plants are due to the presence of secondary metabolites like terpenoids, flavonoids, alkaloids, etc. Anthraquinones represent a group of naturally occurring quinones found generously across various plant species. Anthraquinones attract a significant amount of attention due to their reported efficacy in treating a wide range of diseases. Their complex chemical structures, combined with inherent medicinal properties, underscore their potential as agents for therapy. They demonstrate several therapeutic properties such as laxative, antitumor, antimalarial, antibacterial, antifungal, antioxidant, etc. Anthraquinones are found in different forms (derivatives) in plants, and they exhibit various medicinal properties due to their structure and chemical nature. The precursors for the biosynthesis of anthraquinones in higher plants are provided by different pathways such as plastidic hemiterpenoid 2-C-methyl-D-erthriol4-phosphate (MEP), mevalonate (MVA), isochorismate synthase and polyketide. By conducting a thorough analysis of scientific literature, this review provides insights into the intricate interplay between anthraquinone biosynthesis and its broad-ranging contributions to human health.
摘要:
自古以来,植物已被用作治疗多种疾病的药物。植物的药理特性是由于次级代谢产物如萜类化合物的存在,黄酮类化合物,生物碱,等。蒽醌代表在各种植物物种中大量发现的一组天然存在的醌。蒽醌由于其在治疗多种疾病中的报道功效而引起大量关注。它们复杂的化学结构,结合固有的药用特性,强调了它们作为治疗药物的潜力。他们展示了几种治疗特性,如泻药,抗肿瘤,抗疟药,抗菌,抗真菌药,抗氧化剂,等。蒽醌在植物中以不同的形式(衍生物)被发现,由于它们的结构和化学性质,它们表现出各种药用特性。高等植物中蒽醌生物合成的前体是通过不同的途径提供的,例如质体半类2-C-甲基-D-erthriol4-磷酸酯(MEP),甲羟戊酸(MVA),异氯酸盐合成酶和聚酮。通过对科学文献进行彻底的分析,这篇综述提供了对蒽醌生物合成及其对人类健康的广泛贡献之间复杂相互作用的见解。