Abstract：
When compared to the challenges associated with traditional dosage forms, medication delivery systems based on nanotechnology have been a huge boon. One such candidate for medication delivery is spanlastics, an elastic nanovesicle that can transport a diverse array of medicinal compounds. The use of spanlastics has been associated with an increase in interest in alternative administration methods. The non-ionic surfactant or surfactant blend is the main component of spanlastics. The purpose of this review was primarily to examine the potential of spanlastics as a delivery system for a variety of medication classes administered via diverse routes. Science Direct, Google Scholar, and Pubmed were utilized to search the academic literature for this review. Several studies have demonstrated that spanlastics greatly improve therapeutic effectiveness, increase medication absorption, and decrease drug toxicity. This paper provides a summary of the composition and structure of spanlastics along with their utility in the delivery of various therapeutic agents by adopting different routes. Additionally, it provides an overview of the numerous disorders that may be treated using drugs that are contained in spanlastic vesicles.
摘要：
与传统剂型相关的挑战相比，基于纳米技术的药物输送系统是一个巨大的福音。一种这样的药物输送候选人是痉挛症，一种弹性纳米囊泡，可以运输多种药物。痉挛药的使用与对替代给药方法的兴趣增加有关。非离子表面活性剂或表面活性剂共混物是痉挛剂的主要成分。这篇综述的目的主要是研究痉挛药作为通过多种途径施用的各种药物类别的输送系统的潜力。科学直接，谷歌学者，和Pubmed被用来搜索这篇综述的学术文献。几项研究表明，痉挛疗法大大提高了治疗效果，增加药物吸收，降低药物毒性。本文概述了痉挛剂的组成和结构，以及它们在采用不同途径递送各种治疗剂中的实用性。此外,它提供了许多疾病的概述，可以使用包含在痉挛囊泡中的药物治疗。
