Abstract：
Antiphospholipid Syndrome (APS), characterized by hypercoagulability and pregnancy morbidity, poses a significant clinical challenge when involving organ systems, such as the endocrine system. APS can directly and indirectly influence the anterior and posterior lobes of the pituitary gland. The thyroid gland exhibits involvement, especially in patients with positive anticardiolipin antibodies, yet the clinical significance of the relationship with APS remains elusive. The pancreas, often overlooked, manifests in diverse ways, from pancreatitis to implications in diabetes. Adrenal insufficiency emerges as a common endocrine manifestation of APS, with adrenal hemorrhage or infarction being a presenting manifestation. Adrenal gland involvement has also been reported in the context of catastrophic APS. Pregnancy complications and infertility might be effects of APS on the female ovaries, while testicular torsion and decreased sperm concentration and total sperm count have been reported as rare effects of APS on male testes.
摘要：
抗磷脂综合征(APS),以高凝状态和妊娠发病率为特征，当涉及器官系统时，构成了重大的临床挑战，比如内分泌系统。APS可以直接和间接地影响垂体的前后叶。甲状腺表现出受累，尤其是抗心磷脂抗体阳性的患者，然而，与APS的关系的临床意义仍然难以捉摸。胰腺,经常被忽视,以不同的方式表现，从胰腺炎到糖尿病的影响。肾上腺功能不全是APS的常见内分泌表现，表现为肾上腺出血或梗塞。在灾难性APS的背景下，肾上腺受累也有报道。妊娠并发症和不孕症可能是APS对女性卵巢的影响，据报道，睾丸扭转和精子浓度和精子总数下降是APS对男性睾丸的罕见影响。
