关键词: bladder tumor cyclooxygenase‐2 inhibitor cystitis glandularis preoperative ureteral orifice

来  源:   DOI:10.1002/iju5.12728   PDF(Pubmed)

Abstract:
UNASSIGNED: A previous report has shown that cyclooxygenase-2 inhibitors can prevent the recurrence of cystitis glandularis postoperatively. Herein, we present a case of cystitis glandularis in which the tumor volume was markedly reduced by preoperative oral administration of a cyclooxygenase-2 inhibitor.
UNASSIGNED: A 45-year-old man with voiding difficulty and lower abdominal pain during urination was referred to our hospital. Cystoscopy revealed multiple cystitis glandularis-like edematous masses on the trigone and the neck of the bladder, completely involving the bilateral ureteral orifices. Cyclooxygenase-2 inhibitor was orally administered at the patient\'s request. Six weeks later, the tumor volume was markedly reduced, bilateral ureteral orifices were identified, and the voiding difficulty and pain on urination disappeared. Complete transurethral resection of the residual tumor was performed, and the pathological diagnosis was intestinal-type cystitis glandularis.
UNASSIGNED: Cyclooxygenase-2 inhibition can be considered a useful therapeutic strategy for cystitis glandularis.
摘要:
以前的报告表明,环氧合酶-2抑制剂可以预防术后腺性膀胱炎的复发。在这里,我们介绍了一例腺性膀胱炎,其中通过术前口服环氧合酶-2抑制剂,肿瘤体积显着减小。
一名45岁的男性排尿困难和排尿时的下腹痛被转诊到我们医院。膀胱镜检查发现膀胱三角区和颈部有多发性腺性膀胱炎样水肿肿块,完全累及双侧输尿管口。应患者要求口服环氧合酶-2抑制剂。六周后,肿瘤体积明显缩小,确定双侧输尿管口,排尿困难和排尿疼痛消失了。对残余肿瘤进行经尿道完整切除术,病理诊断为肠型腺性膀胱炎。
环加氧酶-2抑制可以被认为是腺性膀胱炎的有效治疗策略。
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