关键词: diabetes mellitus hypoglycemia insulin paramedics seizures

来  源:   DOI:10.1002/ams2.979   PDF(Pubmed)

Abstract:
UNASSIGNED: Symptomatic hypoglycemia is a common problem in the emergency department (ED). However, without appropriate recognition and management, hypoglycemia remains a potentially fatal condition. The cause of sudden death associated with hypoglycemia might be attributed to cardiac arrhythmias and hypoxia with seizures. Despite advances in diabetes mellitus management and social background, the frequency and characteristics of patients with hypoglycemia-related seizures have remained unknown. Hence, our study aimed to investigate the frequency and characteristics of patients with hypoglycemia presenting with seizures in the ED.
UNASSIGNED: This retrospective observational study was conducted in a single tertiary care center. Patient information was retrieved from the final diagnostic records in the ED. We reviewed all medical records and included patients with symptomatic hypoglycemia aged 16 years or older. The primary outcome was the frequency of seizures in patients with hypoglycemia. We also compared the initial blood sugar levels of the patients with and without seizures.
UNASSIGNED: We included a total of 380 patients (median age, 72 years, IQR 64-80 years; median initial blood sugar, 34 mg/dL, IQR 24-46; 62.9% male). Nineteen of 380 patients (5.0%) had seizures. Although 16 of the 19 patients had diabetes mellitus, none of the 19 patients had a history of epilepsy. The initial blood sugar levels of the patients with and without seizures were not significantly different (p = 0.97).
UNASSIGNED: Approximately 5% of the patients with hypoglycemia presented with seizures. Blood glucose levels of hypoglycemic patients with and without seizures did not differ.
摘要:
症状性低血糖是急诊科(ED)的常见问题。然而,如果没有适当的认可和管理,低血糖仍然是一种潜在的致命疾病.与低血糖相关的猝死原因可能归因于心律失常和癫痫发作的缺氧。尽管在糖尿病管理和社会背景方面取得了进展,低血糖相关癫痫发作患者的频率和特征仍然未知.因此,我们的研究旨在调查ED中出现癫痫发作的低血糖患者的频率和特征.
这项回顾性观察研究是在一家三级护理中心进行的。从ED的最终诊断记录中检索患者信息。我们回顾了所有医疗记录,并纳入了16岁或以上的症状性低血糖患者。主要结果是低血糖患者的癫痫发作频率。我们还比较了有和没有癫痫发作的患者的初始血糖水平。
我们总共纳入了380名患者(中位年龄,72年,IQR64-80岁;初始血糖中位数,34mg/dL,IQR24-46;62.9%男性)。380例患者中有19例(5.0%)癫痫发作。尽管19例患者中有16例患有糖尿病,19例患者均无癫痫史.有和没有癫痫发作的患者的初始血糖水平没有显着差异(p=0.97)。
大约5%的低血糖患者出现癫痫发作。有和没有癫痫发作的低血糖患者的血糖水平没有差异。
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