关键词: esophageal squamous cell carcinoma esophagectomy esophagus lymphatic metastasis neck dissection

来  源:   DOI:10.3892/ol.2024.14519   PDF(Pubmed)

Abstract:
In the present study, the outcomes of elective neck dissection in patients with intrathoracic esophageal squamous cell carcinoma were investigated. From January 2016 to December 2022, 21 patients who underwent esophagectomy and elective neck dissection (both neck level IV) for intrathoracic esophageal squamous cell carcinoma were enrolled. Of these 21 patients, 19 patients were male and 2 were female. A total of 11 patients received concurrent chemoradiotherapy (CCRT) as preoperative treatment. As a result of elective neck dissection at both neck level IV, occult neck metastasis of esophageal squamous cell carcinoma was diagnosed in 3 cases, all of which involved left neck lymph nodes. The incidence of occult neck metastasis was statistically significant in patients with preoperative CCRT, high T stage and high N stage (P<0.05). In addition, 16 out of 21 patients had been under follow-up without disease recurrence after the completion of treatment. However, 3 out of 21 patients succumbed to esophageal squamous cell carcinoma and 2 out of 21 patients were alive with stable disease of esophageal carcinoma. The follow-up period was 19.2±18.4 months. In conclusion, three-field lymph node dissection for intrathoracic esophageal squamous cell carcinoma may be necessary in patients with certain phenotypes, such that collaboration between thoracic surgeons and otolaryngologists may help reduce surgical complications.
摘要:
在本研究中,本文对选择性颈淋巴结清扫术在胸内食管鳞状细胞癌患者中的治疗效果进行了研究。2016年1月至2022年12月,纳入21例因胸内食管鳞状细胞癌行食管切除术和择期颈淋巴结清扫术(均为IV级)的患者。在这21名患者中,男性19例,女性2例。共有11例患者接受同步放化疗(CCRT)作为术前治疗。由于在两个颈部IV级进行了选择性颈部解剖,3例食管鳞癌颈部隐匿性转移,均累及左颈淋巴结。术前CCRT患者颈部隐匿性转移的发生率有统计学意义,高T阶段和高N阶段(P<0.05)。此外,治疗完成后,21例患者中有16例正在接受随访,无疾病复发。然而,21例患者中有3例死于食管鳞癌,21例患者中有2例存活,病情稳定。随访时间为19.2±18.4个月。总之,对于某些表型的患者,胸内食管鳞状细胞癌的三野淋巴结清扫可能是必要的,因此,胸外科医师和耳鼻喉科医师之间的合作可能有助于减少手术并发症。
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