PDF(Pubmed)
Abstract：
The prevalence of neglected tropical diseases, specifically those caused by soil-transmitted helminths (STHs) and other parasites that infest the intestine as part of their life cycle, remains a problem in Indonesia. We assessed the effects of deworming programs and socioeconomic and ecological factors on the incidence rate of infections with STHs and other parasites in an urban area of the Bandung Regency. We recruited 361 children with stunted growth who met the inclusion criteria, and 48 of those children were at high risk of STH infection. The study was conducted between September 2020 and September 2021. We collected possible socioeconomic factors influencing the incidence rate of infections. We found the incidence rate of STH infections among the children with stunted growth to be 3.6%. We confirmed infections with Cyclospora and Cryptosporidium after a Ziehl-Nieelsen stool smear examination in two of the 48 children at risk of infection. We found 43.75% of the children had short stature and weight below the normal limits, while stunting and severe stunting were associated with Ascaris lumbricoides infection (44.70%, p = 0.035). Parents of children with stunted and severely stunted growth were more likely to have a low education level, lack knowledge about deworming program, and to be earning a low income. The mother\'s occupation had a particularly strong influence on the severity of the stunting (89.58%, p = 0.012). Our results show that deworming programs can affect the growth and development of children and that socioeconomic and ecological factors also play a role.
摘要：
被忽视的热带病的流行，特别是由土壤传播的蠕虫（STHs）和其他寄生虫引起的，这些寄生虫作为其生命周期的一部分感染肠道，在印度尼西亚仍然是一个问题。我们评估了驱虫计划以及社会经济和生态因素对万隆摄政区市区STH和其他寄生虫感染发生率的影响。我们招募了361名符合纳入标准的发育迟缓儿童，其中48名儿童感染STH的风险很高。这项研究是在2020年9月至2021年9月之间进行的。我们收集了影响感染发生率的可能的社会经济因素。我们发现STH感染在发育迟缓的儿童中的发生率为3.6％。在有感染风险的48名儿童中，有两名进行Ziehl-Nieelsen粪便涂片检查后，我们确认了环孢菌和隐孢子虫的感染。我们发现43.75%的儿童身材矮小,体重低于正常范围,而发育迟缓和严重发育迟缓与蛔虫感染相关(44.70%，p=0.035)。发育迟缓和严重发育迟缓儿童的父母受教育程度较低,缺乏有关驱虫程序的知识，赚取低收入。母亲的职业对发育迟缓的严重程度有特别强的影响(89.58%，p=0.012)。我们的结果表明，驱虫程序可以影响儿童的生长发育，社会经济和生态因素也起作用。
