Abstract：
BACKGROUND: Alcohol poisoning is a significant global problem that has become an epidemic. The determination of the alcohol type is hereby essential as it may affect the course of the treatment; however, there is no routine laboratory diagnostic method for alcohol types other than for ethanol. In this study, we aimed to define a simple method for alcohol type differentiation by utilizing a combination of breathalyzer and spectrophotometrically measured serum ethanol results.
METHODS: A breathalyzer and spectrophotometry were used to measure four different types of alcohol: ethanol, isopropanol, methanol, and ethylene glycol. To conduct serum alcohol analysis, four serum pools were created, each containing a different type of alcohol. The pools were analyzed using the spectrophotometric method with an enzymatic ethanol test kit. An experiment was conducted to measure the different types of alcohol using impreg-nated cotton and a balloon, simulating a breathalyzer test. An algorithm was created based on the measurements.
RESULTS: Based on the results, the substance consumed could be methanol or isopropanol if the breathalyzer test indicates a positive reading and if the blood ethanol measurement is negative. If both the breathalyzer and the blood measurements are negative, the substance in question may be ethylene glycol.
CONCLUSIONS: This simple method may determine methanol or isopropanol intake. This straightforward and innovative approach could assist healthcare professionals in different fields with diagnosing alcohol intoxication and, more precisely, help reducing related morbidity and mortality.
METHODS: A breathalyzer and spectrophotometry were used to measure four different types of alcohol: ethanol, isopropanol, methanol, and ethylene glycol. To conduct serum alcohol analysis, four serum pools were created, each containing a different type of alcohol. The pools were analyzed using the spectrophotometric method with an enzymatic ethanol test kit. An experiment was conducted to measure the different types of alcohol using impreg-nated cotton and a balloon, simulating a breathalyzer test. An algorithm was created based on the measurements.
RESULTS: Based on the results, the substance consumed could be methanol or isopropanol if the breathalyzer test indicates a positive reading and if the blood ethanol measurement is negative. If both the breathalyzer and the blood measurements are negative, the substance in question may be ethylene glycol.
CONCLUSIONS: This simple method may determine methanol or isopropanol intake. This straightforward and innovative approach could assist healthcare professionals in different fields with diagnosing alcohol intoxication and, more precisely, help reducing related morbidity and mortality.
摘要：
背景：酒精中毒是一个重要的全球性问题，已成为一种流行病。因此，确定酒精类型至关重要，因为它可能会影响治疗过程；但是，除乙醇外，没有针对酒精类型的常规实验室诊断方法。在这项研究中,我们的目的是通过结合呼吸测醉器和分光光度法测定的血清乙醇结果来定义一种简单的酒精类型区分方法。
方法：使用呼吸测醉器和分光光度法测量四种不同类型的酒精：乙醇，异丙醇,甲醇,和乙二醇。进行血清酒精分析，创建了四个血清池，每种都含有不同类型的酒精。使用分光光度法和酶促乙醇测试试剂盒分析池。使用浸渍棉和气球进行了一项实验，以测量不同类型的酒精，模拟酒精测试。基于测量创建算法。
结果：根据结果，如果呼吸测醉器测试表明读数为阳性且血液乙醇测量为阴性，则消耗的物质可能是甲醇或异丙醇。如果呼吸测醉器和血液测量结果都是阴性，该物质可能是乙二醇。
结论：这种简单的方法可以确定甲醇或异丙醇的摄入量。这种简单而创新的方法可以帮助不同领域的医疗保健专业人员诊断酒精中毒，更确切地说,有助于降低相关的发病率和死亡率。
方法：使用呼吸测醉器和分光光度法测量四种不同类型的酒精：乙醇，异丙醇,甲醇,和乙二醇。进行血清酒精分析，创建了四个血清池，每种都含有不同类型的酒精。使用分光光度法和酶促乙醇测试试剂盒分析池。使用浸渍棉和气球进行了一项实验，以测量不同类型的酒精，模拟酒精测试。基于测量创建算法。
结果：根据结果，如果呼吸测醉器测试表明读数为阳性且血液乙醇测量为阴性，则消耗的物质可能是甲醇或异丙醇。如果呼吸测醉器和血液测量结果都是阴性，该物质可能是乙二醇。
结论：这种简单的方法可以确定甲醇或异丙醇的摄入量。这种简单而创新的方法可以帮助不同领域的医疗保健专业人员诊断酒精中毒，更确切地说,有助于降低相关的发病率和死亡率。
