PDF(Pubmed)
Abstract：
OBJECTIVE: Considering the significant prevalence of ileus after abdominal surgery and the beneficial effects of Cuminum cyminum in digestive problems, this study aimed to examine whether Cuminum cyminum has any effect on the return of bowel motility after abdominal surgery.
METHODS: In this triple-blind clinical trial study, 74 patients undergoing abdominal surgery were assigned to the intervention and control groups using minimization methods. The patients in the intervention group consumed 250 mg capsules containing Cuminum cyminum extract 4 h after the surgery and another dose of the drug 1 h afterward. The patients in the control group consumed a 250 mg capsule containing starch as a placebo at hours similar to those in the intervention group. The instruments used to collect the data were a demographic questionnaire and a researcher-made checklist to assess bowel habits. The data were analyzed using SPSS-22 software.
RESULTS: The average time of gas passing in the intervention and control groups was 9.03 ± 3.41 and 11.72 ± 4.21 h, respectively. The defecation times in the intervention and control groups were 16.97 ± 5.02 and 26 ± 9.87 h, showing a significant difference between the two groups as indicated by the independent samples T-test (P > 0.001). Furthermore, abdominal pain, abdominal bloating, nausea, and vomiting were significantly less frequent in the intervention group compared to the control group as confirmed by Fisher\'s exact test (P > 0.001).
CONCLUSIONS: According to the results, the consumption of Cuminum cyminum after abdominal surgery helps to reduce the time of gas passing, defecation, and the return of bowel motility. However, additional studies need to address the effectiveness of Cuminum cyminum by changing the time and duration of its use.
METHODS: In this triple-blind clinical trial study, 74 patients undergoing abdominal surgery were assigned to the intervention and control groups using minimization methods. The patients in the intervention group consumed 250 mg capsules containing Cuminum cyminum extract 4 h after the surgery and another dose of the drug 1 h afterward. The patients in the control group consumed a 250 mg capsule containing starch as a placebo at hours similar to those in the intervention group. The instruments used to collect the data were a demographic questionnaire and a researcher-made checklist to assess bowel habits. The data were analyzed using SPSS-22 software.
RESULTS: The average time of gas passing in the intervention and control groups was 9.03 ± 3.41 and 11.72 ± 4.21 h, respectively. The defecation times in the intervention and control groups were 16.97 ± 5.02 and 26 ± 9.87 h, showing a significant difference between the two groups as indicated by the independent samples T-test (P > 0.001). Furthermore, abdominal pain, abdominal bloating, nausea, and vomiting were significantly less frequent in the intervention group compared to the control group as confirmed by Fisher\'s exact test (P > 0.001).
CONCLUSIONS: According to the results, the consumption of Cuminum cyminum after abdominal surgery helps to reduce the time of gas passing, defecation, and the return of bowel motility. However, additional studies need to address the effectiveness of Cuminum cyminum by changing the time and duration of its use.
摘要：
目的：考虑到腹部手术后肠梗阻的显著患病率以及乌贼在消化问题中的有益作用，这项研究的目的是检查乌贼是否对腹部手术后的肠动力恢复有任何影响。
方法：在这项三盲临床试验研究中，使用最小化方法将74例接受腹部手术的患者分为干预组和对照组。干预组的患者在手术后4小时服用250mg含CuminumCuminum提取物的胶囊，并在手术后1小时服用另一剂量的药物。对照组的患者在与干预组相似的小时内服用了含有淀粉作为安慰剂的250mg胶囊。用于收集数据的工具是人口统计问卷和研究人员制作的检查表，以评估排便习惯。数据采用SPSS-22软件进行分析。
结果：干预组和对照组的平均气体通过时间分别为9.03±3.41和11.72±4.21h，分别。干预组和对照组的排便时间分别为16.97±5.02和26±9.87h,如独立样本T检验所示，两组之间存在显着差异（P>0.001）。此外，腹痛,腹胀,恶心,经Fisher精确检验证实,干预组的呕吐频率明显低于对照组(P>0.001).
结论：根据结果，腹部手术后吃Cuminumcyminum有助于减少气体通过的时间，排便,和肠蠕动的恢复。然而,更多的研究需要通过改变使用时间和持续时间来解决CuminumCuminumCuminum的有效性。
方法：在这项三盲临床试验研究中，使用最小化方法将74例接受腹部手术的患者分为干预组和对照组。干预组的患者在手术后4小时服用250mg含CuminumCuminum提取物的胶囊，并在手术后1小时服用另一剂量的药物。对照组的患者在与干预组相似的小时内服用了含有淀粉作为安慰剂的250mg胶囊。用于收集数据的工具是人口统计问卷和研究人员制作的检查表，以评估排便习惯。数据采用SPSS-22软件进行分析。
结果：干预组和对照组的平均气体通过时间分别为9.03±3.41和11.72±4.21h，分别。干预组和对照组的排便时间分别为16.97±5.02和26±9.87h,如独立样本T检验所示，两组之间存在显着差异（P>0.001）。此外，腹痛,腹胀,恶心,经Fisher精确检验证实,干预组的呕吐频率明显低于对照组(P>0.001).
结论：根据结果，腹部手术后吃Cuminumcyminum有助于减少气体通过的时间，排便,和肠蠕动的恢复。然而,更多的研究需要通过改变使用时间和持续时间来解决CuminumCuminumCuminum的有效性。
