关键词: Anticoagulation Catheter-based thrombectomy Catheter-based thrombolysis Pulmonary embolism Systemic thrombolysis

Mesh : Pulmonary Embolism / therapy diagnosis Humans Practice Guidelines as Topic Risk Assessment / methods Disease Management Risk Factors Thrombolytic Therapy / methods Anticoagulants / therapeutic use

来  源:   DOI:10.1016/j.iccl.2023.08.003

Abstract:
Pulmonary embolism (PE) is a life-threatening condition with increasing hospital admissions. Prompt identification and treatment of PE patients with hemodynamic collapse are essential. Conflicting recommendations and weak evidence hinder effective management of PE, resulting in unchanged mortality rates despite advancements in therapies. Current risk stratification lacks granularity, necessitating a more detailed classification to guide treatment, predict outcomes, and improve patient selection for clinical trials. This article reviews clinical practice guidelines from major North American and European societies, emphasizing the need for more research and guidance to improve mortality and morbidity outcomes in PE.
摘要:
随着住院人数的增加,肺栓塞(PE)是一种危及生命的疾病。及时识别和治疗PE患者的血流动力学塌陷至关重要。相互冲突的建议和薄弱的证据阻碍了体育的有效管理,尽管治疗方法取得了进步,但死亡率保持不变。当前的风险分层缺乏粒度,需要更详细的分类来指导治疗,预测结果,并改善临床试验的患者选择。本文回顾了北美和欧洲主要协会的临床实践指南,强调需要更多的研究和指导,以改善PE的死亡率和发病率。
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