Abstract：
BACKGROUND: Glucosinolates (GSLs) are the most controversial yet ignored class of phytochemicals. These are the middleman phytochemicals that have low bioactivity. But once there is any injury in the plant-manmade, insect caused, or natural-magic happens. The compound is broken down into smaller phytochemicals referred to as glucosinolate hydrolytic products (GHPs; nitriles, isothiocyanates [ITCs], and thiocyanates). These hydrolytic products are like a showstopper of the fashion industry. These compounds have some of the highest bioactivity in nature. They have been associated with a varied range of bioactivities (anticancer, antioxidant, insecticidal, weedicide, etc.) by researchers across the globe.
OBJECTIVE: The objective of the current article is to provide a critical review to highlight some of the important bioactivities of these ignored compounds and for promoting researchers to at least give these compounds a chance-to glow in the dark.
METHODS: This review has been written from analysis of accessible literature, mostly from the last 5 years (2018-2023), with some critically essential exceptions.
RESULTS: The review highlighted a brief background of GSLs and its hydrolysis. Efforts were made to include most of the biological properties of the compound. Special emphasis has been given to the anticancer activities of the compound with details of the involved mechanism.
CONCLUSIONS: Considering the wide array of bioactivities of GHPs, it is essential to consider it as a prospective medicinal compound. More GHPs-in a similar manner as sulforaphane-can be proceeded to phase trials.
CONCLUSIONS: The mechanistic pathway for production of GHPs and related biological activities have been discussed in detail. The bioactivities have been further explained using the involved mechanism.
OBJECTIVE: The objective of the current article is to provide a critical review to highlight some of the important bioactivities of these ignored compounds and for promoting researchers to at least give these compounds a chance-to glow in the dark.
METHODS: This review has been written from analysis of accessible literature, mostly from the last 5 years (2018-2023), with some critically essential exceptions.
RESULTS: The review highlighted a brief background of GSLs and its hydrolysis. Efforts were made to include most of the biological properties of the compound. Special emphasis has been given to the anticancer activities of the compound with details of the involved mechanism.
CONCLUSIONS: Considering the wide array of bioactivities of GHPs, it is essential to consider it as a prospective medicinal compound. More GHPs-in a similar manner as sulforaphane-can be proceeded to phase trials.
CONCLUSIONS: The mechanistic pathway for production of GHPs and related biological activities have been discussed in detail. The bioactivities have been further explained using the involved mechanism.
摘要：
背景：硫代葡萄糖苷是最具争议但被忽视的一类植物化学物质。这些是具有低生物活性的中间植物化学物质。但是一旦人造植物受到任何伤害，昆虫引起的,或者自然的——魔法发生了。该化合物被分解成更小的植物化学物质，称为芥子油苷水解产物（腈，异硫氰酸酯,和硫氰酸盐）。这些水解产物就像时装业的显示塞子。这些化合物具有自然界中最高的生物活性之一。这些与各种生物活性(抗癌，抗氧化剂，杀虫,杀草剂,等)全球研究人员。
目的：本文的目的是提供一个批判性的综述，以强调这些被忽视的化合物的一些重要的生物活性，并促进研究人员至少给这些化合物一个在黑暗中发光的机会。
方法：这篇综述是根据对过去5年（2018-2023年）的可访问文献的分析撰写的，除了一些至关重要的例外。
结果：这篇综述简要介绍了芥子油苷及其水解的背景。努力包括化合物的大部分生物学特性。特别强调了该化合物的抗癌活性，并详细介绍了其相关机制。
结论：考虑到芥子油苷水解产物具有广泛的生物活性，必须将其视为潜在的药用化合物。更多的芥子油苷水解产物-以与萝卜硫烷相似的方式-可以进行阶段试验。
结论：详细讨论了芥子油苷水解产物的产生机理和相关的生物学活性。已经使用所涉及的机制进一步解释了生物活性。
目的：本文的目的是提供一个批判性的综述，以强调这些被忽视的化合物的一些重要的生物活性，并促进研究人员至少给这些化合物一个在黑暗中发光的机会。
方法：这篇综述是根据对过去5年（2018-2023年）的可访问文献的分析撰写的，除了一些至关重要的例外。
结果：这篇综述简要介绍了芥子油苷及其水解的背景。努力包括化合物的大部分生物学特性。特别强调了该化合物的抗癌活性，并详细介绍了其相关机制。
结论：考虑到芥子油苷水解产物具有广泛的生物活性，必须将其视为潜在的药用化合物。更多的芥子油苷水解产物-以与萝卜硫烷相似的方式-可以进行阶段试验。
结论：详细讨论了芥子油苷水解产物的产生机理和相关的生物学活性。已经使用所涉及的机制进一步解释了生物活性。
