TGF β 1 调节基于心球的体外心脏血管周围小生境的细胞组成。
关键词: TGFβ1 cardiospheres cell microenvironment endothelium perivascular niche
Mesh : Transforming Growth Factor beta1 / pharmacology metabolism Cell Differentiation / drug effects Humans Cell Proliferation / drug effects Human Umbilical Vein Endothelial Cells / metabolism drug effects Animals Microfilament Proteins / metabolism genetics Platelet Endothelial Cell Adhesion Molecule-1 / metabolism Cadherins / metabolism Laminin / metabolism pharmacology Muscle Proteins / metabolism Cells, Cultured Endothelial Cells / metabolism drug effects cytology Fibronectins / metabolism pharmacology Antigens, CD / metabolism Myocardium / metabolism cytology Stem Cell Niche / drug effects physiology Collagen Type I / metabolism Spheroids, Cellular / drug effects metabolism cytology Cell Culture Techniques, Three Dimensional / methods
来 源: DOI:10.1007/s10517-024-06142-8