Abstract:
Objectives - postmenopausal women (PMW) undergo a physiological phase of lack or insufficient female sex hormones resulting in some consequences including hematological deficits. The present study aimed to investigate the detection of anemia in postmenopausal women using easy laboratory tools. In this retrospective analysis of patient data collected during the period between 2014-2022. Data retrieved from PMW records were collected over 4 years and analyzed. In comparison to normal ranges, data of PMW has shown reduced levels of hemoglobin, packed cell volume, mean corpuscular volume, and mean corpuscular hemoglobin. PMW has also shown elevated levels of red cell distribution width and levels of serum iron. Compared to normal ranges, no changes have been seen regarding red blood cell count, Mean corpuscular hemoglobin concentration, unsaturated or total iron binding capacity, transferrin saturation, serum ferritin, white blood cells count, and platelets. To provide in-depth investigation, we divide our participants into three groups according to their ages: 45-55 years, 56-65 years, and 66-80 years. The older the age, the more parameters are altered. The study highlighted the potential impact of postmenopausal hormone alteration on hematological parameters and the routine laboratory tools could be used to assess such alteration in blood parameters.
摘要:
目标-绝经后妇女(PMW)经历了缺乏或不足的女性性激素的生理阶段,导致一些后果,包括血液学缺陷。本研究旨在研究使用简单的实验室工具检测绝经后妇女的贫血。在对2014-2022年期间收集的患者数据的回顾性分析中。从PMW记录中检索的数据收集并分析了4年。与正常范围相比,PMW的数据显示血红蛋白水平降低,细胞体积,平均红细胞体积,和平均红细胞血红蛋白。PMW还显示红细胞分布宽度和血清铁水平升高。与正常范围相比,红细胞计数没有变化,平均红细胞血红蛋白浓度,不饱和或总铁结合能力,转铁蛋白饱和度,血清铁蛋白,白细胞计数,和血小板。进行深入的调查,我们根据参与者的年龄将他们分为三组:45-55岁,56-65岁,66-80岁。年龄越大,更多的参数被改变。该研究强调了绝经后激素改变对血液学参数的潜在影响,并且常规实验室工具可用于评估血液参数的这种改变。