Abstract：
This systematic review aimed to compare the histological response of inflamed pulpodentinal complex to the hydraulic calcium silicate cements in experimental animal models of pulpitis. Articles that evaluated the histological response of inflamed pulp to mineral trioxide aggregate (MTA) in comparison with other restorative materials were selected and analysed in detail. The risk of bias assessment was conducted using SYRCLE\'s RoB tool. The GRADEpro tool was used to determine the overall quality of evidence. Out of the 2947 retrieved articles from databases, five articles fulfilled the inclusion criteria. MTA induced significantly more hard tissue formation compared to calcium hydroxide. The use of pulp-capping material containing fluocinolone acetonide and ASP/PLGA-ASP/ACP/PLLA-PLGA composite membrane was comparable. This systematic review could not demonstrate enhanced efficiency of capping materials compared to MTA. Future well-conducted animal studies are warranted for demonstrating the hard tissue formation abilities of pulp-capping materials with convenient inflammatory conditions.
摘要：
本系统综述旨在比较牙髓炎实验动物模型中发炎的牙髓复合物与水硬性硅酸钙水泥的组织学反应。选择并详细分析了与其他修复材料相比，评估发炎纸浆对三氧化二矿聚集体（MTA）的组织学反应的文章。使用SYRCLE的RoB工具进行偏倚风险评估。GRADepro工具用于确定证据的总体质量。在从数据库检索到的2947篇文章中，五篇文章符合纳入标准。与氢氧化钙相比,MTA诱导显著更多的硬组织形成。使用含氟轻松酮和ASP/PLGA-ASP/ACP/PLLA-PLGA复合膜的制浆材料具有可比性。与MTA相比，该系统综述无法证明封端材料的效率更高。未来进行良好的动物研究是必要的，以证明在方便的炎症条件下，盖髓材料的硬组织形成能力。
