关键词: TDM recommendations healthcare team compliance pediatric oncology personalized medication management personalized medicine precision medicine vancomycin

来  源:   DOI:10.1080/17410541.2024.2360386

Abstract:
Aim: Vancomycin, a crucial treatment for Gram-positive bacteria, necessitates therapeutic drug monitoring (TDM) to prevent treatment failures. We investigated the healthcare professional\'s compliance toward TDM of vancomycin recommendations and follow-up levels. Materials & methods: We collected data from 485 patients who received vancomycin in the Children\'s Cancer Hospital Egypt 57357 medical records system (Cerner) over 4 months, from January to April 2020. Results: Our data shows that only 54% of patients had TDM requests from healthcare professionals for the total patients who received vancomycin treatment. The healthcare professionals\' compliance with the recommendations was 91.7%, while the follow-up levels were 66.7%. Conclusion: While overall adherence to recommendations is strong, enhancing compliance with follow-up levels remains a priority for improvement.
[Box: see text].
摘要:
目的:万古霉素,革兰氏阳性细菌的关键治疗方法,需要治疗药物监测(TDM)以防止治疗失败。我们调查了医疗保健专业人员对万古霉素建议和随访水平的TDM的依从性。材料与方法:我们收集了485名在埃及儿童肿瘤医院接受万古霉素治疗的患者的数据57357医疗记录系统(Cerner)超过4个月,2020年1月至4月。结果:我们的数据显示,对于接受万古霉素治疗的所有患者,只有54%的患者有医疗保健专业人员的TDM请求。医疗保健专业人员对建议的遵守率为91.7%,而随访水平为66.7%。结论:虽然总体上对建议的依从性很强,加强对后续行动水平的遵守仍然是需要改进的优先事项。
[方框:见正文]。
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