关键词: O-heterocycles S-heterocycles Visible light functionalization green procedure synthesis

来  源:   DOI:10.2174/0115680266313243240624071549

Abstract:
Visible-light-mediated reactions have recently emerged as a powerful strategy for the synthesis of diverse organic molecules under mild reaction conditions. Usually, the reactions are performed at room temperature and thus sensitive functional groups remain unaffected. Thus, this protocol has received intense interest from academia as well as industries. The heterocycles, in general, are of much interest because of their biological activities and application in therapeutics. The Oxygen- and Sulfur-containing heterocyclic compounds have recently attracted attention as these compounds showed promising activities as anti-cancer drugs, antibiotics, antifungal and anti-inflammatory agents among other applications. The synthesis of this class of compounds by efficient and greener routes has become an important target. This review highlights the various procedures for the synthesis of these compounds and their derivatives under visible light-induced reactions. The green aspects and mechanism of each procedure have been discussed.
摘要:
可见光介导的反应最近已成为在温和反应条件下合成多种有机分子的有力策略。通常,反应在室温下进行,因此敏感官能团保持不受影响。因此,该协议受到了学术界和工业界的强烈兴趣。杂环,总的来说,由于它们的生物活性和在治疗中的应用而引起了极大的兴趣。含氧和含硫杂环化合物最近引起了人们的关注,因为这些化合物显示出作为抗癌药物的有希望的活性,抗生素,抗真菌和抗炎药在其他应用。通过有效和更绿色的途径合成这类化合物已成为重要的目标。这篇综述强调了在可见光诱导的反应下合成这些化合物及其衍生物的各种程序。讨论了每个程序的绿色方面和机制。
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