关键词: Upper gastrointestinal tract cytoreductive surgery neoadjuvant chemotherapy ovarian cancer pancreaticoduodenectomy

来  源:   DOI:10.21873/cdp.10347   PDF(Pubmed)

Abstract:
UNASSIGNED: Upper gastrointestinal obstruction is an extremely rare complication of primary ovarian cancer. We present a case of primary advanced ovarian cancer with gastroduodenal obstruction successfully managed with neoadjuvant chemotherapy (NAC) and conservative treatment.
UNASSIGNED: A 60-year-old woman was referred to our hospital for advanced ovarian cancer with upper gastrointestinal obstruction. Computed tomography and endoscopy revealed severe duodenal obstruction caused by dissemination. NAC was initiated with conservative management using a nasogastric tube and total parenteral nutrition (TPN). She was able to eat and TPN was stopped after three months. Complete resection was achieved with interval debulking surgery (IDS) not involving pancreatoduodenectomy, which would have been necessary for primary debulking surgery. There were no serious postoperative complications.
UNASSIGNED: NAC with conservative management can improve upper gastrointestinal obstruction in patients with primary advanced ovarian cancer. Furthermore, IDS is expected to allow complete resection, avoiding highly invasive surgeries.
摘要:
上消化道梗阻是原发性卵巢癌极为罕见的并发症。我们介绍了一例原发性晚期卵巢癌合并胃十二指肠梗阻的病例,该病例通过新辅助化疗(NAC)和保守治疗成功治疗。
一名60岁妇女因晚期卵巢癌合并上消化道梗阻被转诊至我院。计算机断层扫描和内窥镜检查显示扩散引起的严重十二指肠梗阻。NAC是通过使用鼻胃管和全胃肠外营养(TPN)的保守管理开始的。她能够进食,三个月后停止了TPN。通过不涉及胰十二指肠切除术的间隔减积手术(IDS)实现了完全切除,这对于初次减瘤手术是必要的。术后无严重并发症发生。
NAC保守治疗可改善原发性晚期卵巢癌患者上消化道梗阻。此外,IDS预计允许完全切除,避免高侵入性手术。
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