PDF(Pubmed)
Abstract：
Plasma or serum amino acids are used to evaluate nutritional status and metabolic disorders. In this study, we aimed to set reference values of serum amino acid concentrations in the Noma horse, a Japanese native horse. Thirty-one horses were classified into six age groups: neonatal foal (0-4 days), foal (0.5-1 years), youth (5 years), middle age (10 years), old (15 years), and extra-old (>20 years). Horses >5 years of age were analyzed together as the adult group. In the adult horses, there were no significant differences among the serum amino acid concentrations of each age group. The foal group had higher concentrations of alanine, aspartic acid, glutamic acid, α-aminoadipic acid, and 3-methyl-histidine than the adult group. The neonatal foal group had higher serum concentrations of phenylalanine, lysine, alanine, proline, aspartic acid, glutamic acid, β-alanine, and β-amino-iso-butyric acid and lower tryptophan concentrations and Fischer\'s ratios than the adult group. The neonatal foal group had higher β-amino-iso-butyric acid concentrations and lower tryptophan and 3-methyl-histidine concentrations than the foal group. Therefore, reference values might be set separately in neonatal foals, foals, and adult horses. The data for the serum amino acid concentrations can be used for health care through physiological and pathological evaluations in Noma horses.
摘要：
血浆或血清氨基酸用于评估营养状况和代谢紊乱。在这项研究中,我们的目的是设定Noma马血清氨基酸浓度的参考值，日本本土的马。31匹马被分为六个年龄组：新生马驹（0-4天），小马驹（0.5-1年），青年（5岁）中年（10岁），年龄（15岁），和超老（>20年）。将年龄>5岁的马一起作为成年组进行分析。在成年马中，各年龄组的血清氨基酸浓度无显著差异。马驹组丙氨酸浓度较高，天冬氨酸,谷氨酸，α-氨基己二酸,和3-甲基组氨酸比成人组。新生马驹组血清苯丙氨酸浓度较高，赖氨酸，丙氨酸,脯氨酸,天冬氨酸,谷氨酸，β-丙氨酸,和β-氨基异丁酸，色氨酸浓度和费休比率低于成年组。与马驹组相比，新生马驹组的β-氨基异丁酸浓度较高，色氨酸和3-甲基组氨酸浓度较低。因此,参考值可以在新生儿小马驹中单独设置，小马驹,成年马血清氨基酸浓度的数据可通过对Noma马的生理和病理评估用于医疗保健。
