PDF(Pubmed)
Abstract：
Systemic chemotherapy is the standard treatment for non-small cell lung cancer with distant metastases. However, additional local treatment for brain and thoracic lesions is recommended for patients with synchronous solitary brain metastases (SSBM). We report the case of a 71-year-old male diagnosed with pulmonary adenocarcinoma and SSBM. Pathological examination of the brain metastasis showed positive immunostaining for programmed cell death ligand 1 expression. After four cycles of chemotherapy with immune checkpoint inhibitors, right upper lobectomy with ND2a-1 was performed. Pathological examination revealed complete pathological response, and this patient is expected to experience long-term survival.
摘要：
全身化疗是非小细胞肺癌远处转移的标准治疗方法。然而,对于同步孤立性脑转移(SSBM)的患者,建议对脑和胸廓病变进行额外的局部治疗.我们报告了一名71岁的男性，诊断为肺腺癌和SSBM。脑转移的病理学检查显示，程序性细胞死亡配体1表达的免疫染色阳性。免疫检查点抑制剂化疗四个周期后，用ND2a-1进行右上叶切除术。病理检查显示完全病理反应，该患者有望长期生存。
