关键词: ART HIV Recurrent anemia acyclovir herpes genitalis

Mesh : Humans Female Pregnancy Acyclovir / therapeutic use adverse effects administration & dosage HIV Infections / drug therapy complications Anemia Pregnancy Complications, Infectious / drug therapy Antiviral Agents / adverse effects therapeutic use Adult Recurrence Uganda Treatment Outcome Herpes Genitalis / drug therapy Blood Transfusion

来  源:   DOI:10.4314/ahs.v24i1.11   PDF(Pubmed)

Abstract:
This case report describes a pregnant patient with recent diagnosis of Human Immuno-Deficiency Virus (HIV) infection initiated on Anti-Retroviral Therapy (ART) in the second trimester, as well as high dose acyclovir high for large infected genital warts. She had no other HIV related opportunistic infections, and no prior anti tuberculosis treatment or preventive medication. Despite little response to acyclovir, patient was continuing on acyclovir for over 4 months. She subsequently developed recurrent anemia requiring frequent transfusion (14 units in total) over a 6-week period. On stopping acyclovir, the anemia subsided, a few weeks later she had a normal delivery, followed by surgical removal of the warts. At a follow-up 8 months later, she was well, with a healthy baby, and reported no other episodes of blood transfusion.
摘要:
本病例报告描述了一名妊娠中期在抗逆转录病毒治疗(ART)中开始的最近诊断为人类免疫缺陷病毒(HIV)感染的孕妇,以及高剂量阿昔洛韦高用于大型感染生殖器疣。她没有其他与艾滋病毒相关的机会性感染,事先没有抗结核治疗或预防性药物。尽管对阿昔洛韦反应不大,患者继续服用阿昔洛韦超过4个月.随后,她出现了复发性贫血,需要在6周内频繁输血(总共14个单位)。在停止阿昔洛韦的时候,贫血消退了,几周后她正常分娩,然后手术切除疣.在8个月后的随访中,她很好,一个健康的宝宝,并报告没有其他输血事件。
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