PDF(Pubmed)
Abstract：
UNASSIGNED: Pain is a common yet undertreated symptom of Parkinson\'s disease (PD). This study investigated the effect of Gua Sha therapy on pain in patients with PD.
UNASSIGNED: A total of 56 PD patients with pain were randomized into either the experimental group (n=28), receiving 12 sessions of Gua Sha therapy, or the control group (n=28) without additional treatment. Participants underwent assessment at baseline, after the twelfth invention, and at the 2-month follow-up timepoints. The primary outcome was KPPS and VAS. Secondary outcomes included UPDRS I-III, PDSS-2, HADS, PDQ-39, and blood biomarkers (5-HT, IL-8, IL-10).
UNASSIGNED: The experimental group reported a significant improvement in pain severity, motor functions, affective disorder, and sleep quality (P < 0.05). Furthermore, increasing trends in both 5-HT and IL-10, as well as decreasing trends in IL-8 were observed. No serious adverse events occurred.
UNASSIGNED: The preliminary findings suggest that Gua Sha therapy may be effective and safe for alleviating pain and improving other disease-related symptoms in PD patients.
UNASSIGNED: A total of 56 PD patients with pain were randomized into either the experimental group (n=28), receiving 12 sessions of Gua Sha therapy, or the control group (n=28) without additional treatment. Participants underwent assessment at baseline, after the twelfth invention, and at the 2-month follow-up timepoints. The primary outcome was KPPS and VAS. Secondary outcomes included UPDRS I-III, PDSS-2, HADS, PDQ-39, and blood biomarkers (5-HT, IL-8, IL-10).
UNASSIGNED: The experimental group reported a significant improvement in pain severity, motor functions, affective disorder, and sleep quality (P < 0.05). Furthermore, increasing trends in both 5-HT and IL-10, as well as decreasing trends in IL-8 were observed. No serious adverse events occurred.
UNASSIGNED: The preliminary findings suggest that Gua Sha therapy may be effective and safe for alleviating pain and improving other disease-related symptoms in PD patients.
摘要：
疼痛是帕金森病(PD)的一种常见但治疗不足的症状。这项研究调查了刮沙疗法对PD患者疼痛的影响。
■共有56名PD疼痛患者被随机分为任一实验组（n=28），接受了12次刮沙治疗，或对照组（n=28），无需额外治疗。参与者在基线时接受评估，在第十二发明之后，在2个月的随访时间点。主要结果是KPPS和VAS。次要结果包括UPDRSI-III，PDSS-2,HADS,PDQ-39和血液生物标志物(5-HT，IL-8、IL-10)。
■实验组报告疼痛严重程度显著改善，电机功能,情感障碍,睡眠质量(P<0.05)。此外，观察到5-HT和IL-10的增加趋势以及IL-8的减少趋势。无严重不良事件发生。
■初步研究结果表明，瓜沙疗法对于缓解PD患者的疼痛和改善其他疾病相关症状可能是有效和安全的。
■共有56名PD疼痛患者被随机分为任一实验组（n=28），接受了12次刮沙治疗，或对照组（n=28），无需额外治疗。参与者在基线时接受评估，在第十二发明之后，在2个月的随访时间点。主要结果是KPPS和VAS。次要结果包括UPDRSI-III，PDSS-2,HADS,PDQ-39和血液生物标志物(5-HT，IL-8、IL-10)。
■实验组报告疼痛严重程度显著改善，电机功能,情感障碍,睡眠质量(P<0.05)。此外，观察到5-HT和IL-10的增加趋势以及IL-8的减少趋势。无严重不良事件发生。
■初步研究结果表明，瓜沙疗法对于缓解PD患者的疼痛和改善其他疾病相关症状可能是有效和安全的。
