PDF(Pubmed)
Abstract：
Fibrosis is a pathological process involving the abnormal deposition of connective tissue, resulting from improper tissue repair in response to sustained injury caused by hypoxia, infection, or physical damage. It can impact any organ, leading to their dysfunction and eventual failure. Additionally, tissue fibrosis plays an important role in carcinogenesis and the progression of cancer.Early and accurate diagnosis of organ fibrosis, coupled with regular surveillance, is essential for timely disease-modifying interventions, ultimately reducing mortality and enhancing quality of life. While extensive research has already been carried out on the topics of aberrant wound healing and fibrogenesis, we lack a thorough understanding of how their relationship reveals itself through modern imaging techniques.This paper focuses on fibrosis of the genito-urinary system, detailing relevant imaging technologies used for its detection and exploring future directions.
摘要：
纤维化是涉及结缔组织异常沉积的病理过程,由于缺氧造成的持续损伤导致组织修复不当，感染,或物理损伤。它可以影响任何器官，导致他们的功能障碍和最终的失败。此外,组织纤维化在癌症的发生和发展中起着重要作用。早期准确诊断器官纤维化,再加上定期监测，对于及时的疾病改善干预措施至关重要，最终降低死亡率，提高生活质量。虽然已经对异常伤口愈合和纤维发生进行了广泛的研究，我们对他们之间的关系如何通过现代成像技术揭示自己缺乏透彻的了解。本文的重点是生殖泌尿系统的纤维化，详细介绍用于其检测的相关成像技术，并探索未来的方向。
