PDF(Pubmed)
Abstract：
BACKGROUND: Schwannomas are benign usually encapsulated nerve sheath tumors derived from the Schwann cells, and affecting single or multiple nerves. The tumors commonly arise from the cranial nerves as acoustic neurinomas but they are extremely rare in the pelvis and the retroperitoneal area. Retroperitoneal pelvic schwannomas often present with non-specific symptoms leading to misdiagnosis and prolonged morbidity.
METHODS: We report the case of a 59-year-old woman presenting with a feeling of heaviness in the lower abdomen who was found to have a retroperitoneal pelvic schwannoma originating from the right femoral nerve. She had a history of two resections of peripheral schwannomas at four different sites of limbs. After conducting magnetic resonance imaging, this pelvic schwannoma was misdiagnosed as a gynecological malignancy. The tumor was successfully removed by laparoscopic surgery. Pathological analysis of the mass revealed a benign schwannoma of the femoral nerve sheath with demonstrating strong, diffuse positivity for S-100 protein.
CONCLUSIONS: Although retroperitoneal pelvic schwannoma is rare, it should be considered in the differential diagnosis of pelvic masses, especially in patients with a history of neurogenic mass or the presence of neurogenic mass elsewhere.
METHODS: We report the case of a 59-year-old woman presenting with a feeling of heaviness in the lower abdomen who was found to have a retroperitoneal pelvic schwannoma originating from the right femoral nerve. She had a history of two resections of peripheral schwannomas at four different sites of limbs. After conducting magnetic resonance imaging, this pelvic schwannoma was misdiagnosed as a gynecological malignancy. The tumor was successfully removed by laparoscopic surgery. Pathological analysis of the mass revealed a benign schwannoma of the femoral nerve sheath with demonstrating strong, diffuse positivity for S-100 protein.
CONCLUSIONS: Although retroperitoneal pelvic schwannoma is rare, it should be considered in the differential diagnosis of pelvic masses, especially in patients with a history of neurogenic mass or the presence of neurogenic mass elsewhere.
摘要：
背景：神经鞘瘤是良性的，通常来自雪旺氏细胞的包裹性神经鞘瘤，影响单个或多个神经。肿瘤通常起源于颅神经作为听神经瘤，但在骨盆和腹膜后区域极为罕见。腹膜后盆腔神经鞘瘤通常表现为非特异性症状，导致误诊和延长发病率。
方法：我们报告了一例59岁女性，下腹部有沉重的感觉，被发现患有源自右股神经的腹膜后骨盆神经鞘瘤。她在四肢的四个不同部位有两次切除周围神经鞘瘤的病史。进行磁共振成像后，该盆腔神经鞘瘤被误诊为妇科恶性肿瘤。通过腹腔镜手术成功切除肿瘤。肿块的病理分析显示股神经鞘良性神经鞘瘤，表现出强烈，S-100蛋白的弥漫性阳性。
结论：尽管腹膜后盆腔神经鞘瘤很少见，在鉴别诊断盆腔肿块时应考虑，特别是在有神经源性肿块病史或其他地方存在神经源性肿块的患者中。
方法：我们报告了一例59岁女性，下腹部有沉重的感觉，被发现患有源自右股神经的腹膜后骨盆神经鞘瘤。她在四肢的四个不同部位有两次切除周围神经鞘瘤的病史。进行磁共振成像后，该盆腔神经鞘瘤被误诊为妇科恶性肿瘤。通过腹腔镜手术成功切除肿瘤。肿块的病理分析显示股神经鞘良性神经鞘瘤，表现出强烈，S-100蛋白的弥漫性阳性。
结论：尽管腹膜后盆腔神经鞘瘤很少见，在鉴别诊断盆腔肿块时应考虑，特别是在有神经源性肿块病史或其他地方存在神经源性肿块的患者中。
