Abstract:
Metalloproteins play a crucial role in regulating different aspects of the immune system in humans. They have various functions in immunity, including recognizing and presenting antigens, aiding in the movement and effectiveness of immune cells, and facilitating interactions between the host and pathogens. Understanding how these proteins work can help us develop new methods to control the immune response in different diseases. Metalloproteins contain metal ions in their structure, which allows them to perform these diverse functions. They encompass a wide range of enzymes, signaling molecules, and structural proteins that utilize metal ions as cofactors for their activities. Examples of metalloproteins include superoxide dismutase, catalase, and metalloproteases, which regulate oxidative stress, inflammation, and tissue remodelling processes associated with immune activation. By studying their functions and the effects of their dysfunction, researchers can develop strategies to improve immune function and combat various diseases. This review explores the diverse functions of metalloproteins in immune processes, highlighting their significance in both health and disease.
摘要:
金属蛋白在调节人类免疫系统的不同方面中起着至关重要的作用。它们具有各种免疫功能,包括识别和呈递抗原,帮助免疫细胞的运动和有效性,促进宿主和病原体之间的相互作用。了解这些蛋白质是如何工作的,可以帮助我们开发新的方法来控制不同疾病的免疫反应。金属蛋白在其结构中含有金属离子,这使得他们能够执行这些不同的功能。它们包含各种各样的酶,信号分子,和利用金属离子作为其活性的辅因子的结构蛋白。金属蛋白的例子包括超氧化物歧化酶,过氧化氢酶,和金属蛋白酶,调节氧化应激,炎症,和与免疫激活相关的组织重塑过程。通过研究它们的功能和功能障碍的影响,研究人员可以制定改善免疫功能和对抗各种疾病的策略。这篇综述探讨了金属蛋白在免疫过程中的多种功能,强调它们在健康和疾病中的重要性。