关键词: Obstetrics and gynaecology Pregnancy

Mesh : Humans Female Pregnancy Factor X Deficiency / diagnosis complications Adult Cesarean Section Oligohydramnios Pregnancy Complications, Hematologic / diagnosis Pregnancy Outcome Fetal Distress / etiology

来  源:   DOI:10.1136/bcr-2023-259458

Abstract:
Factor X (FX) is a vitamin K-dependent enzyme, which acts as an important coagulation factor of coagulation cascade. FX deficiency is an autosomal recessive inherited disease and is often demonstrated in families with consanguity. Pregnancy in women with congenital FX deficiency has been associated with adverse fetal outcomes. We report a case of pregnancy in women with FX deficiency. The patient needed an immediate caesarean section at 38 weeks of gestation because of severe oligohydramnios and fetal distress. FX deficiency during pregnancy was effectively managed, leading to a positive outcome through the optimal utilisation of available resources.
摘要:
因子X(FX)是一种维生素K依赖性酶,作为凝血级联的重要凝血因子。FX缺乏症是一种常染色体隐性遗传性疾病,通常在有血缘关系的家庭中表现出来。先天性FX缺乏症妇女的妊娠与不良胎儿结局有关。我们报告了一例FX缺乏症女性怀孕的病例。由于严重的羊水过少和胎儿窘迫,患者在妊娠38周时需要立即剖腹产。怀孕期间外汇缺乏得到有效管理,通过优化利用可用资源,从而取得积极成果。
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