Abstract：
BACKGROUND: Pleural effusions in post-operative thoracic surgery patients are common. Effusions can result in prolonged hospitalizations or readmissions, with prior studies suggesting mixed effects of pleural drainage on hypoxia. We aimed to define the impact of pleural drainage on pulse oximetry (SpO2) in post-thoracic surgery patients.
METHODS: A retrospective study of post-operative thoracic surgery patients undergoing pleural drainage was performed. SpO2 and supplemental oxygen (FiO2) values were recorded at pre- and post-procedure. The primary outcome was difference in pre-procedural and post-procedural SpO2.
RESULTS: We identified 95 patients with a mean age of 65 (SD - 13.8) years undergoing 122 pleural drainage procedures. Mean drainage volume was 619 (SD-423) mL and the majority of procedures (88.5 %) included a drainage of <1000 mL. SpO2 was associated with an increase from 94.0 % (SD-2.6) to 97.3 % (SD-2.0) at 24-h (p < 0.0001). FiO2 was associated with a decrease from 0.31 (SD-0.15) to 0.29 (SD-0.12) at 24-h (p = 0.0081). SpO2/FiO2 was associated with an increase from 344.5 (SD-99.0) to 371.9 (SD-94.7) at 24-h post-procedure (p < 0.0001).
CONCLUSIONS: Pleural drainage within post-operative thoracic surgery patients offers statistically significant improvements in oxygen saturation by peripheral pulse oximetry and oxygen supplementation; however the clinical significance of these changes remains unclear. Pleural drainage itself may be requested for numerous reasons, including diagnostic (fevers, leukocytosis, etc.) or therapeutic (worsening dyspnea) evaluation. However, pleural drainage may offer minimal clinical impact on pulse oximetry in post-operative thoracic surgery patients.
METHODS: A retrospective study of post-operative thoracic surgery patients undergoing pleural drainage was performed. SpO2 and supplemental oxygen (FiO2) values were recorded at pre- and post-procedure. The primary outcome was difference in pre-procedural and post-procedural SpO2.
RESULTS: We identified 95 patients with a mean age of 65 (SD - 13.8) years undergoing 122 pleural drainage procedures. Mean drainage volume was 619 (SD-423) mL and the majority of procedures (88.5 %) included a drainage of <1000 mL. SpO2 was associated with an increase from 94.0 % (SD-2.6) to 97.3 % (SD-2.0) at 24-h (p < 0.0001). FiO2 was associated with a decrease from 0.31 (SD-0.15) to 0.29 (SD-0.12) at 24-h (p = 0.0081). SpO2/FiO2 was associated with an increase from 344.5 (SD-99.0) to 371.9 (SD-94.7) at 24-h post-procedure (p < 0.0001).
CONCLUSIONS: Pleural drainage within post-operative thoracic surgery patients offers statistically significant improvements in oxygen saturation by peripheral pulse oximetry and oxygen supplementation; however the clinical significance of these changes remains unclear. Pleural drainage itself may be requested for numerous reasons, including diagnostic (fevers, leukocytosis, etc.) or therapeutic (worsening dyspnea) evaluation. However, pleural drainage may offer minimal clinical impact on pulse oximetry in post-operative thoracic surgery patients.
摘要：
背景：胸外科手术后胸腔积液很常见。积液可导致长期住院或再次入院，先前的研究表明胸膜引流对缺氧的混合作用。我们旨在定义胸膜引流对胸外科术后患者脉搏血氧饱和度（SpO2）的影响。
方法：对胸外科术后患者进行胸腔引流的回顾性研究。在手术前和手术后记录SpO2和补充氧气(FiO2)值。主要结果是术前和术后SpO2的差异。
结果：我们确定了95例患者，平均年龄65（SD=13.8）岁，接受122例胸腔引流手术。平均引流体积为619（SD-423）mL，大多数程序（88.5％）包括<1000mL的引流。在24小时时,SpO2从94.0%(SD-2.6)增加到97.3%(SD-2.0)(p<0.0001)。FiO2在24小时时从0.31（SD-0.15）降低到0.29（SD-0.12）（p=0.0081）。术后24小时SpO2/FiO2从344.5(SD-99.0)增加到371.9(SD-94.7)(p<0.0001)。
结论：胸腔镜手术后患者的胸腔引流通过外周脉搏血氧饱和度和氧补充可显著改善血氧饱和度，但这些变化的临床意义尚不清楚。胸膜引流本身可能有很多原因，包括诊断(发烧，白细胞增多,等。)或治疗性(呼吸困难恶化)评估。然而,胸腔引流对胸外科手术后患者脉搏血氧饱和度的临床影响最小.
方法：对胸外科术后患者进行胸腔引流的回顾性研究。在手术前和手术后记录SpO2和补充氧气(FiO2)值。主要结果是术前和术后SpO2的差异。
结果：我们确定了95例患者，平均年龄65（SD=13.8）岁，接受122例胸腔引流手术。平均引流体积为619（SD-423）mL，大多数程序（88.5％）包括<1000mL的引流。在24小时时,SpO2从94.0%(SD-2.6)增加到97.3%(SD-2.0)(p<0.0001)。FiO2在24小时时从0.31（SD-0.15）降低到0.29（SD-0.12）（p=0.0081）。术后24小时SpO2/FiO2从344.5(SD-99.0)增加到371.9(SD-94.7)(p<0.0001)。
结论：胸腔镜手术后患者的胸腔引流通过外周脉搏血氧饱和度和氧补充可显著改善血氧饱和度，但这些变化的临床意义尚不清楚。胸膜引流本身可能有很多原因，包括诊断(发烧，白细胞增多,等。)或治疗性(呼吸困难恶化)评估。然而,胸腔引流对胸外科手术后患者脉搏血氧饱和度的临床影响最小.
