Abstract：
BACKGROUND: The management of chronic wounds presents a challenge for surgeons. In this pilot study, the authors established a novel auto-grafting approach for chronic wounds and evaluated its efficacy.
OBJECTIVE: The objective of this pilot study was to observe the clinical efficacy of granulation-embedded skin grafting for the treatment of chronic wounds at high altitudes.
METHODS: The data of 45 patients with chronic wounds were obtained from the medical records of the Yushu People\'s Hospital. Patients were divided into stamp skin-grafting and granulation-embedded skin-grafting groups. Skin graft survival rate, wound coverage rate, and wound-healing time were observed and recorded. The length of hospital stay and 1% total body surface area (TBSA) treatment cost were compared.
RESULTS: Significant differences were noted in skin graft survival rate (94% ± 3% vs 86% ± 3%, P < .01), wound coverage rate on postoperative day 7 (61% ± 16% vs 54% ± 18%, P < .01), and wound-healing times (23 ± 2.52 days vs 31 ± 3.61 days, P < .05). The length of hospital stay and 1% TBSA treatment cost were significantly reduced in the granulation-embedded skin grafting group (P < .05).
CONCLUSIONS: Granulation-embedded skin grafting can improve the healing of chronic wounds at high altitudes. These findings provide a new approach to the clinical treatment of chronic wounds.
OBJECTIVE: The objective of this pilot study was to observe the clinical efficacy of granulation-embedded skin grafting for the treatment of chronic wounds at high altitudes.
METHODS: The data of 45 patients with chronic wounds were obtained from the medical records of the Yushu People\'s Hospital. Patients were divided into stamp skin-grafting and granulation-embedded skin-grafting groups. Skin graft survival rate, wound coverage rate, and wound-healing time were observed and recorded. The length of hospital stay and 1% total body surface area (TBSA) treatment cost were compared.
RESULTS: Significant differences were noted in skin graft survival rate (94% ± 3% vs 86% ± 3%, P < .01), wound coverage rate on postoperative day 7 (61% ± 16% vs 54% ± 18%, P < .01), and wound-healing times (23 ± 2.52 days vs 31 ± 3.61 days, P < .05). The length of hospital stay and 1% TBSA treatment cost were significantly reduced in the granulation-embedded skin grafting group (P < .05).
CONCLUSIONS: Granulation-embedded skin grafting can improve the healing of chronic wounds at high altitudes. These findings provide a new approach to the clinical treatment of chronic wounds.
摘要：
背景：慢性伤口的处理对外科医生提出了挑战。在这项试点研究中，作者建立了一种新的慢性伤口自体移植方法，并评估了其疗效。
目的：本试验的目的是观察植骨植皮治疗高原慢性创面的临床疗效。
方法：45例慢性伤口患者的资料来源于玉树市人民医院的病历。患者分为邮票植皮和肉芽包埋植皮组。植皮成活率,伤口覆盖率,观察并记录创面愈合时间。比较住院时间和1％的总体表面积（TBSA）治疗费用。
结果：皮肤移植成活率存在显著差异（94%±3%vs86%±3%，P<.01),术后第7天伤口覆盖率（61%±16%vs54%±18%，P<.01),和伤口愈合时间（23±2.52天vs31±3.61天，P<0.05)。肉芽包埋植皮组的住院时间和1％TBSA治疗费用明显减少（P<0.05）。
结论：颗粒包埋植皮可以改善高海拔地区慢性伤口的愈合。这些发现为慢性伤口的临床治疗提供了新的方法。
目的：本试验的目的是观察植骨植皮治疗高原慢性创面的临床疗效。
方法：45例慢性伤口患者的资料来源于玉树市人民医院的病历。患者分为邮票植皮和肉芽包埋植皮组。植皮成活率,伤口覆盖率,观察并记录创面愈合时间。比较住院时间和1％的总体表面积（TBSA）治疗费用。
结果：皮肤移植成活率存在显著差异（94%±3%vs86%±3%，P<.01),术后第7天伤口覆盖率（61%±16%vs54%±18%，P<.01),和伤口愈合时间（23±2.52天vs31±3.61天，P<0.05)。肉芽包埋植皮组的住院时间和1％TBSA治疗费用明显减少（P<0.05）。
结论：颗粒包埋植皮可以改善高海拔地区慢性伤口的愈合。这些发现为慢性伤口的临床治疗提供了新的方法。
