靶向 IL - 1 控制难治性毛发红斑糠疹。
Mesh : Humans Pityriasis Rubra Pilaris / drug therapy pathology genetics Interleukin-1beta / metabolism antagonists & inhibitors Interleukin 1 Receptor Antagonist Protein / therapeutic use Keratinocytes / metabolism drug effects pathology Antibodies, Monoclonal, Humanized / therapeutic use pharmacology Male NF-kappa B / metabolism Nod2 Signaling Adaptor Protein / metabolism genetics antagonists & inhibitors Female CARD Signaling Adaptor Proteins / metabolism genetics Skin / pathology metabolism drug effects Interleukin-1 / antagonists & inhibitors metabolism genetics Middle Aged Guanylate Cyclase / metabolism antagonists & inhibitors genetics Adult Signal Transduction / drug effects Membrane Proteins
来 源:
DOI:10.1126/sciadv.ado2365
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