Abstract：
Studies on alterations in inflammatory markers and risk factors for perforation in hydatid cysts of the lung are rare. In our study, we planned to investigate the effect of inflammatory markers on prognosis of hydatid cyst disease. 37 patients underwent surgery for pulmonary hydatid cyst between February 2022 and October 2023 and analyzed retrospectively. Inflammatory markers were calculated from preoperative and postoperative 3rd-month peripheral blood results. Cyst size was 58.5 ± 28.0 mm, 5 patients had bilateral cysts and 11 patients had multifocal cysts. Preoperative white blood cell, white blood cell difference, preoperative and postoperative eosinophils, preoperative neutrophils, neutrophils difference, preoperative systemic immune inflammatory index, systemic immune inflammatory index difference and preoperative eosinophil lymphocyte ratio were higher in patients with perforated cysts, the cut-off value for preoperative white blood cell for perforation was 10,535, preoperative cut-off value for eosinophils was 230, preoperative cut-off value for neutrophils was 8815, the cut-off value for preoperative systemic immune inflammatory index was 1129.83 and the cut-off value for preoperative eosinophil-lymphocyte ratio was 0.09. In patients with preoperative eosinophil, neutrophil, white blood cell, eosinophil-lymphocyte ratio and systemic immune inflammatory index values above the cut-off value, the probability of perforation increased 7.5, 13.6, 6.3, 9.6, and 9.3 times, respectively.
摘要：
关于肺部包虫囊肿中炎症标志物和穿孔危险因素变化的研究很少。在我们的研究中,我们计划研究炎症标志物对包虫囊肿疾病预后的影响。对2022年2月至2023年10月37例肺包虫囊肿手术患者进行回顾性分析。根据术前和术后3个月的外周血结果计算炎症标志物。囊肿大小为58.5±28.0mm，5例患者有双侧囊肿，11例患者有多灶性囊肿。术前白细胞,白细胞区别,术前和术后嗜酸性粒细胞，术前中性粒细胞，中性粒细胞差异，术前全身免疫炎症指标，囊肿穿孔患者全身免疫炎症指标差异及术前嗜酸性粒细胞淋巴细胞比例较高,术前白细胞穿孔的截断值为10535,嗜酸性粒细胞的截断值为230,中性粒细胞的截断值为8815,全身免疫炎症指数的截断值为1129.83,嗜酸性粒细胞与淋巴细胞比值的截断值为0.09.在术前嗜酸性粒细胞的患者中，中性粒细胞,白细胞,嗜酸性粒细胞-淋巴细胞比值和全身免疫炎症指标值高于临界值，穿孔的概率增加了7.5、13.6、6.3、9.6和9.3倍，分别。
