Abstract：
OBJECTIVE: Temporomandibular disorders (TMDs) are usually treated with occlusal appliances and supportive treatments such as physical therapy and drugs. Supplements can be included among potential supportive therapies, with the aim of reducing the use of drugs. To evaluate the efficacy of nutraceuticals\' short-term treatment in subjects with temporomandibular disorders.
METHODS: The study started in January 2021 and ended in January 2022. Subjects with temporomandibular disorders and a verbal numeric scale >40 were recruited and randomly assigned to one of the following groups. If waiting to start a therapy, to the nutraceutical group or to the no treatment group, while if already undergoing splint therapy, to nutraceautical+splint group or to splint therapy group. Nutraceutical used was composed by Boswellia Serrata Casperome, Magnesium, Tryptophan and vitamins B2 and D with a posology of one tablet/day before sleep for 40 days. Presence of temporomandibular pain, headache, neck pain and sleep/emotional disorders were assessed at T0 and at T1, after 40 days. ANOVA was performed to compare treatments with nutraceuticals and their respective controls, as for the variables related to painful symptomatology. Chi- Squared was conducted to assess differences in sleep/emotional disorders between groups. The statistical significance was p<0.05.
RESULTS: The groups using nutraceuticals showed statistically significant improvements over controls for most of the variables analyzed.
CONCLUSIONS: The use of nutraceutical seems to be a valuable support for TMD therapy in the short term either alone or combined with occlusal splint therapy.
METHODS: The study started in January 2021 and ended in January 2022. Subjects with temporomandibular disorders and a verbal numeric scale >40 were recruited and randomly assigned to one of the following groups. If waiting to start a therapy, to the nutraceutical group or to the no treatment group, while if already undergoing splint therapy, to nutraceautical+splint group or to splint therapy group. Nutraceutical used was composed by Boswellia Serrata Casperome, Magnesium, Tryptophan and vitamins B2 and D with a posology of one tablet/day before sleep for 40 days. Presence of temporomandibular pain, headache, neck pain and sleep/emotional disorders were assessed at T0 and at T1, after 40 days. ANOVA was performed to compare treatments with nutraceuticals and their respective controls, as for the variables related to painful symptomatology. Chi- Squared was conducted to assess differences in sleep/emotional disorders between groups. The statistical significance was p<0.05.
RESULTS: The groups using nutraceuticals showed statistically significant improvements over controls for most of the variables analyzed.
CONCLUSIONS: The use of nutraceutical seems to be a valuable support for TMD therapy in the short term either alone or combined with occlusal splint therapy.
摘要：
目的：颞下颌关节紊乱病（TMD）通常采用咬合矫治器和支持治疗，如物理治疗和药物治疗。补充剂可以包括在潜在的支持疗法中，目的是减少药物的使用。评价对颞下颌关节紊乱病患者短期治疗的疗效。
方法：该研究于2021年1月开始，并于2022年1月结束。招募患有颞下颌关节紊乱病和言语数字量表>40的受试者，并将其随机分配到以下组中。如果等待开始治疗，营养药组或无治疗组，而如果已经接受夹板治疗,营养保健+夹板组或夹板治疗组。使用的营养保健品由BoswelliaSerrataCasperome组成，镁，色氨酸和维生素B2和D，睡前40天，每天一片。颞下颌疼痛的存在，头痛,在40天后,在T0和T1时评估颈部疼痛和睡眠/情绪障碍.进行方差分析以比较与营养食品及其各自对照的治疗方法。至于与疼痛症状学相关的变量。进行一次平方以评估组间睡眠/情绪障碍的差异。统计学意义为p<0.05。
结果：在分析的大多数变量中，使用营养品的组比对照组有统计学上的显着改善。
结论：无论是单独使用或与咬合夹板疗法联合使用，短期使用营养食品似乎都是TMD治疗的有价值的支持。
方法：该研究于2021年1月开始，并于2022年1月结束。招募患有颞下颌关节紊乱病和言语数字量表>40的受试者，并将其随机分配到以下组中。如果等待开始治疗，营养药组或无治疗组，而如果已经接受夹板治疗,营养保健+夹板组或夹板治疗组。使用的营养保健品由BoswelliaSerrataCasperome组成，镁，色氨酸和维生素B2和D，睡前40天，每天一片。颞下颌疼痛的存在，头痛,在40天后,在T0和T1时评估颈部疼痛和睡眠/情绪障碍.进行方差分析以比较与营养食品及其各自对照的治疗方法。至于与疼痛症状学相关的变量。进行一次平方以评估组间睡眠/情绪障碍的差异。统计学意义为p<0.05。
结果：在分析的大多数变量中，使用营养品的组比对照组有统计学上的显着改善。
结论：无论是单独使用或与咬合夹板疗法联合使用，短期使用营养食品似乎都是TMD治疗的有价值的支持。
