PDF(Pubmed)
Abstract：
Export of secretory cargoes from the endoplasmic reticulum (ER) requires COPII proteins, which were first identified for their ability to coat small vesicles that bud from the ER. Recent data indicate that COPII proteins can also organize into a collar at the necks of tubules, as well as phase-separate into liquid-like condensates. Thus, COPII assemblies seem to be tailored to accommodate variations in the size and quantities of cargo secreted.
摘要：
从内质网（ER）出口分泌的货物需要COPII蛋白，首先被鉴定为具有覆盖从ER芽的小囊泡的能力。最近的数据表明，COPII蛋白也可以在小管的颈部组织成项圈，以及相分离成液体状冷凝物。因此，COPII组件似乎是定制的，以适应所分泌货物的大小和数量的变化。
