Abstract：
A novel Fe2Mo3O8/MoO2@MoS2 nanocomposite is synthesized for extremely sensitive detection of NH3 in the breath of kidney disease patients at room temperature. Compared to MoS2, α-Fe2O3/MoS2, and MoO2@MoS2, it shows the optimal gas-sensing performance by optimizing the formation of Fe2Mo3O8 at 900 °C. The annealed Fe2Mo3O8/MoO2@MoS2 nanocomposite (Fe2Mo3O8/MoO2@MoS2-900 °C) sensor demonstrates a remarkably high selectivity of NH3 with a response of 875% to 30 ppm NH3 and an ultralow detection limit of 3.7 ppb. This sensor demonstrates excellent linearity, repeatability, and long-term stability. Furthermore, it effectively differentiates between patients at varying stages of kidney disease through quantitative NH3 measurements. The sensing mechanism is elucidated through the analysis of alterations in X-ray photoelectron spectroscopy (XPS) signals, which is supported by density functional theory (DFT) calculations illustrating the NH3 adsorption and oxidation pathways and their effects on charge transfer, resulting in the conductivity change as the sensing signal. The excellent performance is mainly attributed to the heterojunction among MoS2, MoO2, and Fe2Mo3O8 and the exceptional adsorption and catalytic activity of Fe2Mo3O8/MoO2@MoS2-900 °C for NH3. This research presents a promising new material optimized for detecting NH3 in exhaled breath and a new strategy for the early diagnosis and management of kidney disease.
摘要：
合成了一种新型的Fe2Mo3O8/MoO2@MoS2纳米复合材料，用于在室温下极其灵敏地检测肾脏疾病患者呼吸中的NH3。与MoS2，α-Fe2O3/MoS2和MoO2@MoS2相比，通过在900°C下优化Fe2Mo3O8的形成，显示出最佳的气敏性能。退火的Fe2Mo3O8/MoO2@MoS2纳米复合材料（Fe2Mo3O8/MoO2@MoS2-900°C）传感器显示出非常高的NH3选择性，对30ppmNH3的响应为875％，检测限为3.7ppb的超低。该传感器具有出色的线性度，重复性,和长期稳定。此外，它通过定量的NH3测量有效区分不同阶段的肾脏疾病患者。通过分析X射线光电子能谱（XPS）信号的变化来阐明传感机制，这得到了密度泛函理论（DFT）计算的支持，该计算说明了NH3吸附和氧化途径及其对电荷转移的影响，导致电导率变化作为传感信号。优异的性能主要归因于MoS2，MoO2和Fe2Mo3O8之间的异质结以及Fe2Mo3O8/MoO2@MoS2-900°C对NH3的出色吸附和催化活性。这项研究提出了一种有前途的新材料，用于检测呼出气中的NH3，并为肾脏疾病的早期诊断和管理提供了新的策略。
