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Abstract：
Background Spinal metastatic disease is a silent progressive cancer complication with an increasing prevalence worldwide. The spine is the third most common site where solid tumors metastasize. Complications involved in spinal metastasis include root or spinal cord compression, progressing to a declining quality of life as patient autonomy reduces and pain increases. The main objective of this study is to report the incidence of patients and typology of spinal metastases in three reference centers in Mexico. Methodology Retrospective cohorts of patients diagnosed with spinal metastases from January 2010 to February 2017 at the National Cancer Institute, National Rehabilitation Institute, and the Traumatology and Orthopedics Hospital \"Lomas Verdes\" in Mexico City were analyzed. Results A total of 326 patients (56% males) with spinal metastases were reported. The mean age was 58.06 ± 14.05 years. The main sources of spinal metastases were tumors of unknown origin in 53 (16.25%) cases, breast cancer in 67 (20.5%) cases, prostate cancer in 59 (18%) cases, myeloma in 24 (7.4%) cases, and lung cancer in 23 (7.1%) cases. Conclusions The data obtained in this analysis delivers an updated standpoint on Mexico, providing the opportunity to distinguish the current data from global references. Collecting more epidemiological information for better recording of cancer and its associated complications, as well as further studies on them, is necessary.
摘要：
背景脊柱转移性疾病是一种无症状的进行性癌症并发症，在全球范围内患病率越来越高。脊柱是实体肿瘤转移的第三大最常见部位。脊柱转移的并发症包括根部或脊髓压迫，随着患者自主性降低和疼痛增加，生活质量下降。这项研究的主要目的是报告墨西哥三个参考中心的脊柱转移的患者发生率和类型。方法回顾性研究2010年1月至2017年2月在美国国家癌症研究所诊断为脊柱转移的患者队列，国家康复研究所，和墨西哥城的创伤和骨科医院“LomasVerdes”进行了分析。结果脊柱转移瘤326例(56%为男性)。平均年龄58.06±14.05岁。脊柱转移瘤的主要来源为不明原因的肿瘤53例(16.25%),乳腺癌67例（20.5%），59例（18%）前列腺癌，24例（7.4%）骨髓瘤，23例(7.1%)肺癌。结论本分析获得的数据提供了关于墨西哥的最新观点，提供区分当前数据与全球参考的机会。收集更多的流行病学信息，以便更好地记录癌症及其相关并发症，以及对它们的进一步研究，是必要的。
