关键词: carcinoma of unknown primary (cup) cervical lymphadenopathy head and neck cancer surgery neoplasm recurrence oncology and critical care

来  源:   DOI:10.7759/cureus.58537   PDF(Pubmed)

Abstract:
Metastatic cervical carcinoma from an unknown primary source poses a diagnostic and therapeutic challenge, as it involves the spread of cancer to the neck lymph nodes without a discernible primary tumor despite thorough investigation. While the diagnosis and treatment of this uncommon condition lack definitive evidence, a review of existing literature offers some clinical guidance. A comprehensive diagnostic evaluation, which includes multiple imaging and endoscopic studies, is essential. Surgery is preferred whenever feasible due to its ability to offer more precise staging. This treatment entails an excisional biopsy, neck dissection, and tonsillectomy, but advanced cases necessitate a combination of treatments. This case report underscores this complexity, where, despite radical neck dissection on the affected side, recurrence manifested after two months with no discernible primary site. We emphasize the urgency for continued research and innovative approaches to enhance the diagnosis and management of metastatic cervical carcinoma from an unknown primary source.
摘要:
来自未知原发的转移性宫颈癌提出了诊断和治疗挑战,因为它涉及癌症扩散到颈部淋巴结,尽管进行了彻底的调查,但没有明显的原发性肿瘤。虽然这种罕见疾病的诊断和治疗缺乏明确的证据,对现有文献的回顾提供了一些临床指导.全面的诊断评估,其中包括多种成像和内窥镜研究,是必不可少的。只要可行,手术是首选,因为它能够提供更精确的分期。这种治疗需要切除活检,颈淋巴结清扫术,扁桃体切除术,但是晚期病例需要联合治疗。这份病例报告强调了这种复杂性,where,尽管在患侧进行了彻底的颈部解剖,2个月后复发,没有明显的原发部位。我们强调迫切需要继续研究和创新方法,以从未知的原发来源加强转移性宫颈癌的诊断和管理。
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