PDF(Pubmed)
Abstract：
UNASSIGNED: Operations for malignant diseases of the bile duct, pancreas, and esophagus are the most invasive gastroenterological surgeries. The frequency of complications after these surgeries is high, which affects the postoperative course and mortality. In patients who undergo these types of surgeries, continuous monitoring of the perioperative central venous oxygen saturation (ScvO2) is possible via a central venous catheter. We aimed to investigate the relationship between continuously monitored perioperative ScvO2 values and postoperative complications.
UNASSIGNED: The medical records of 115 patients who underwent highly invasive gastroenterological surgeries and ScvO2 monitoring from April 2012 to March 2014 were analyzed. Sixty patients met the inclusion criteria, and their ScvO2 levels were continuously monitored perioperatively. The relationship between ScvO2 levels and major postoperative complications, defined as Clavien-Dindo grade ≥ III, was examined using uni- and multivariate analysis.
UNASSIGNED: Thirty patients developed major postoperative complications. The adequate cut-off value derived from receiver operating curves of the postoperative average ScvO2 levels for predicting major complications was 75%. Multivariate analysis revealed that low average postoperative ScvO2 levels (p = 0.016) and blood loss ≥ 1000 mL (p = 0.039) were significant predictors of major postoperative complications.
UNASSIGNED: Low perioperative ScvO2 values were associated with an increased risk of major postoperative complications. Continuous ScvO2 monitoring will help prevent postoperative complications.
UNASSIGNED: The medical records of 115 patients who underwent highly invasive gastroenterological surgeries and ScvO2 monitoring from April 2012 to March 2014 were analyzed. Sixty patients met the inclusion criteria, and their ScvO2 levels were continuously monitored perioperatively. The relationship between ScvO2 levels and major postoperative complications, defined as Clavien-Dindo grade ≥ III, was examined using uni- and multivariate analysis.
UNASSIGNED: Thirty patients developed major postoperative complications. The adequate cut-off value derived from receiver operating curves of the postoperative average ScvO2 levels for predicting major complications was 75%. Multivariate analysis revealed that low average postoperative ScvO2 levels (p = 0.016) and blood loss ≥ 1000 mL (p = 0.039) were significant predictors of major postoperative complications.
UNASSIGNED: Low perioperative ScvO2 values were associated with an increased risk of major postoperative complications. Continuous ScvO2 monitoring will help prevent postoperative complications.
摘要：
■胆管恶性疾病的手术，胰腺,食管是最有侵入性的胃肠手术。这些手术后并发症的频率很高，影响术后病程和死亡率。在接受这些类型手术的患者中，可以通过中心静脉导管连续监测围手术期中心静脉血氧饱和度(ScvO2).我们旨在研究围手术期持续监测的ScvO2值与术后并发症之间的关系。
■分析了2012年4月至2014年3月进行了高侵入性胃肠手术和ScvO2监测的115例患者的病历。60例患者符合纳入标准，围手术期持续监测其ScvO2水平。ScvO2水平与术后主要并发症的关系,定义为Clavien-Dindo等级≥III，使用单因素和多因素分析进行了检查。
■30例患者出现了严重的术后并发症。从术后平均ScvO2水平的接受者操作曲线得出的预测主要并发症的适当临界值为75％。多因素分析显示，术后平均ScvO2水平低（p=0.016）和失血量≥1000mL（p=0.039）是术后主要并发症的重要预测因素。
■低的围手术期ScvO2值与主要术后并发症的风险增加相关。持续的ScvO2监测将有助于预防术后并发症。
■分析了2012年4月至2014年3月进行了高侵入性胃肠手术和ScvO2监测的115例患者的病历。60例患者符合纳入标准，围手术期持续监测其ScvO2水平。ScvO2水平与术后主要并发症的关系,定义为Clavien-Dindo等级≥III，使用单因素和多因素分析进行了检查。
■30例患者出现了严重的术后并发症。从术后平均ScvO2水平的接受者操作曲线得出的预测主要并发症的适当临界值为75％。多因素分析显示，术后平均ScvO2水平低（p=0.016）和失血量≥1000mL（p=0.039）是术后主要并发症的重要预测因素。
■低的围手术期ScvO2值与主要术后并发症的风险增加相关。持续的ScvO2监测将有助于预防术后并发症。
