PDF(Pubmed)
Abstract：
Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous disorder. Tubers of the central nervous system are a hallmark of the disorder and often cause epilepsy. Many TSC patients fail to achieve seizure control with medication alone. Several case series have demonstrated high seizure freedom rates after resective surgery. However, the technique for the resection of epileptogenic tubers has largely been unreported. Here the authors present 2 cases to illustrate their multistage approach for localizing and resecting the seizure onset zone in patients with TSC. At their institution, they have excellent seizure outcomes and a low complication rate with this technique. The video can be found here: https://stream.cadmore.media/r10.3171/2024.4.FOCVID2411.
摘要：
结节性硬化症（TSC）是一种常染色体显性神经皮肤疾病。中枢神经系统的块茎是该疾病的标志，通常会引起癫痫。许多TSC患者单独使用药物无法实现癫痫发作控制。几例病例系列显示，切除手术后癫痫发作的自由度很高。然而,切除致癫痫块茎的技术在很大程度上没有报道。在这里，作者介绍了2例病例，以说明他们在TSC患者中定位和切除癫痫发作区的多阶段方法。在他们的机构，他们有良好的癫痫发作结果和低并发症发生率与这项技术。视频可以在这里找到：https://stream。cadmore.媒体/r10.3171/2024.4。FOCVID2411.
