关键词: chronic cortical epilepsy neuromodulation stimulation subthreshold

来  源:   DOI:10.3171/2024.4.FOCVID2422   PDF(Pubmed)

Abstract:
Neurostimulation is an increasingly common treatment option for medically intractable epilepsy. SANTE (Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy) and Responsive Neurostimulation (RNS) System are landmark neurostimulation trials that utilized either duty cycle or a responsive stimulation paradigm. A seizure-free outcome is rarely observed with responsive and duty cycle neurostimulation devices. Chronic subthreshold cortical stimulation (CSCS) is a promising treatment for adult drug-resistant epilepsy involving eloquent cortex and has demonstrated safety and efficacy. Herein, the authors describe the surgical technique as well as details of stimulation programming involved in CSCS placement to facilitate the adoption of this promising treatment. The video can be found here: https://stream.cadmore.media/r10.3171/2024.4.FOCVID2422.
摘要:
神经刺激是医学上难治性癫痫的越来越常见的治疗选择。SANTE(癫痫丘脑前核的刺激)和响应性神经刺激(RNS)系统是具有里程碑意义的神经刺激试验,利用占空比或响应性刺激范例。反应性和占空比神经刺激设备很少观察到无癫痫发作的结果。慢性阈下皮质刺激(CSCS)是成人耐药性癫痫的一种有前途的治疗方法,涉及雄辩的皮质,并已证明其安全性和有效性。在这里,作者描述了CSCS放置过程中涉及的手术技术以及刺激编程的细节,以促进这种有前景的治疗的采用.视频可以在这里找到:https://stream。cadmore.媒体/r10.3171/2024.4。FOCVID2422.
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