关键词: case report infectious disease neurology neurosyphilis optic neuropathy syphilis treponema pallidum

来  源:   DOI:10.7759/cureus.49299   PDF(Pubmed)

Abstract:
Neurosyphilis, a rare manifestation of Treponema pallidum spreading into the central nervous system, is a critical differential diagnosis due to its potentially severe neurologic effects if left untreated. We present a case of a 37-year-old woman who complained of bilateral vision loss and headaches originally concerning for idiopathic intracranial hypertension and uncontrolled diabetes. Comprehensive evaluations eventually led to a neurosyphilis diagnosis. Ophthalmologic examination revealed multifactorial visual symptoms with diabetic retinopathy contributing alongside neurosyphilis. Treatment was started promptly at the time of diagnosis and resulted in improvement in visual symptoms. This case emphasizes the importance of syphilis screening in appropriate age ranges, even in low-prevalence areas. Recognition of neurosyphilis as a potential diagnosis can impact patient outcomes and highlights the need for continued vigilance to identify the disease.
摘要:
神经梅毒,梅毒螺旋体传播到中枢神经系统的一种罕见表现,是关键的鉴别诊断,因为如果不治疗,其潜在的严重神经系统影响。我们介绍了一例37岁的妇女,她抱怨双侧视力丧失和头痛,最初是由于特发性颅内高压和不受控制的糖尿病。综合评估最终导致神经梅毒诊断。眼科检查显示糖尿病视网膜病变的多因素视觉症状以及神经梅毒。在诊断时迅速开始治疗并导致视觉症状的改善。这个案例强调了在适当年龄范围内进行梅毒筛查的重要性,即使在低流行地区。将神经梅毒视为潜在的诊断可能会影响患者的预后,并强调需要继续保持警惕以识别该疾病。
公众号