Mesh : Pregnancy Humans Female Prenatal Exposure Delayed Effects Child Nervous System / drug effects growth & development Persistent Organic Pollutants Maternal Exposure / adverse effects Halogenated Diphenyl Ethers / toxicity Hydrocarbons, Chlorinated Child Development / drug effects Environmental Pollutants / toxicity

来  源:   DOI:10.3760/cma.j.cn112150-20231028-00299

Abstract:
Persistent Organic Pollutants (POPs) have the characteristics of resistance to environmental degradation, bioaccumulation and long-distance migration potential. Maternal exposure to POPs during pregnancy can enter the fetal blood circulation through the placental barrier, and have a potential impact on the functional development of the nervous system of the offspring. This in turn leads to the occurrence and development of neurological defects and diseases in adulthood. The purpose of this paper is to elucidate the effects of exposure to three major POPs (organochlorine compounds, perfluoroalkyl and polyfluoroalkyl substances, and polybrominated diphenyl ethers) during pregnancy on the functional development of the nervous system (social emotions, cognition, language, exercise, and adaptability) in children, and to provide reference for subsequent studies.
持久性有机污染物(POPs)具有抵抗环境降解性、生物蓄积性和远距离迁移潜力等特点,母亲孕期POPs暴露可通过胎盘屏障进入胎儿血液循环,对子代的神经系统功能发育产生潜在影响,进而导致成人期神经系统功能缺陷和疾病的发生发展。本文旨在阐明孕期暴露于3种主要POPs(有机氯化合物、全氟及多氟烷基物质和多溴联苯醚)对儿童神经系统功能发育(社会情绪、认知、语言、运动和适应性)的影响,为后续相关研究提供参考依据。.
摘要:
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