Abstract：
Photoaging is a complex, ongoing process that clinically manifests as cutaneous rhytides, atrophy, laxity, dyspigmentation, telangiectasias, roughness, and mottled appearance of the skin. There is an abundance of research establishing the mechanism of ultraviolet (UV) - induced photodamage as it is a significant source of photoaging and skin cancers. While UV damage is known to induce photoaging, it is important to understand how other forms of light radiation also contribute to this process. UV only constitutes 5 to 10% of solar radiation that reaches the earth\'s surface. The remaining nearly 90% is evenly split between infrared and visible light radiation. Early research shows that varied skin types may elicit different photobiologic responses to light. This article presents the mechanisms and biomarkers of photodamage induced by light from across the spectrum, including UV, visible light, and infrared to better prevent and reverse the damage of photoaging in all skin types.J Drugs Dermatol. 2024;23(7):504-509. doi:10.36849/JDD.7438.
摘要：
光老化是一个复杂的，正在进行的过程，临床表现为皮肤癣，萎缩,松弛，色素沉着,毛细血管扩张,粗糙度,和斑驳的皮肤外观。有大量的研究建立了紫外线（UV）诱导的光损伤的机制，因为它是光老化和皮肤癌的重要来源。虽然已知紫外线损伤会引起光老化，重要的是要了解其他形式的光辐射如何也有助于这一过程。紫外线仅占到达地球表面的太阳辐射的5％至10％。剩余的近90％在红外和可见光辐射之间平均分配。早期研究表明，不同的皮肤类型可能会引起对光的不同光生物学反应。本文介绍了光引起的光损伤的机制和生物标志物，包括UV,可见光,和红外线，以更好地预防和逆转所有皮肤类型的光老化的损害。J药物Dermatol.2024；23（7）：504-509。doi:10.36849/JD.7438。
